The purpose of this article is to show how globalization processes contributed to the decline of national institutions in the selection and development of Swiss business elites, drawing from empirical data from two recent research projects. The first database contains profile characteristics of CEOs and chairmen from 110 biggest Swiss companies over a 30 years period. The second database contains information collected in 2009 on profiles and careers of more than 900 top managers working for more than 100 multinational corporations in four countries (France, Germany, United Kingdom and Switzerland). The analysis of our data allows us to illustrate and describe the globalization of profiles and the decline of national and traditional elements. The Swiss case can be brought in perspective and compared with other countries, in particular with France.