Variations of the carcinoembryonic antigen level in the plasma of patients with gynecologie cancers during therapy

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Etat: Public
Version: Final published version
ID Serval
serval:BIB_C120C73C5102
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Variations of the carcinoembryonic antigen level in the plasma of patients with gynecologie cancers during therapy
Périodique
American Journal of Obstetrics and Gynecology
Auteur(s)
Barrelet V., Mach J.P.
ISSN
0002-9378
Statut éditorial
Publié
Date de publication
1975
Volume
121
Numéro
2
Pages
164-168
Langue
anglais
Résumé
In 63 patients with histologically proved gynecologie carcinoma, circulating carcinoembryonic antigen (CEA) was determined by radioimmunoassay before and at two intervals after treatment. Thirty-one patients of 63 had CEA values over 2.5 ng. per milliliter before treatment. In general, the CEA levels were low compared to those found in endodermal carcinoma. The percentage of elevated CEA values was slightly higher in cases of carcinoma of the cervix and corpus uteri than in those of carcinoma of the ovary. All patients with CEA levels greater than 2.5 ng. per milliliter treated by complete surgical resection of tumor showed a drop of CEA levels to below 2.5 ng. per milliliter seven weeks after operation. In contrast, patients with palliative therapy showed no change in CEA values. About half of the patients treated with a complete course of internal and external radiotherapy showed a drop of CEA levels to below 2.5 ng. per milliliter, whereas the
other patients showed fluctuating CEA values. No correlation between clinical status and
evolution of CEA levels in these patients could be drawn at the present time. The CEA test
seems to be of little value for the earl of diagnosis of gynecologie carcinoma but appears
to be interesting for the evaluation of therapy and the follow-up of patients with diagnosed
cases.
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Création de la notice
25/04/2013 10:01
Dernière modification de la notice
20/08/2019 15:35
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