Reactivity of antiglioma monoclonal antibodies for a large panel of cultured gliomas and other neuroectoderm derived tumors.

Détails

ID Serval
serval:BIB_BD9C9E12C333
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Reactivity of antiglioma monoclonal antibodies for a large panel of cultured gliomas and other neuroectoderm derived tumors.
Périodique
Anticancer Research
Auteur(s)
de Muralt B., de Tribolet N., Diserens A.C., Carrel S., Mach J.P.
ISSN
0250-7005 (Print)
ISSN-L
0250-7005
Statut éditorial
Publié
Date de publication
1983
Volume
3
Numéro
1
Pages
1-6
Langue
anglais
Résumé
We produced three monoclonal antibodies, BF7, GE2 and CG12, against cultured human glioma cells. Their specificity was tested by an indirect antibody-binding radioimmunoassay on a panel of glial and non-glial tumor cell lines. BF7 and GE2 react preferentially with glioma cells and, except for one colon carcinoma line, they do not bind to the control non-neuroectodermal cells; they appear to be directed against common malignant glioma associated antigens. CG12, the third monoclonal antibody, binds to the great majority of tumor cell lines of neuroectodermal origin and does not bind to any other cell lines tested.
Mots-clé
Animals, Antibodies, Monoclonal/immunology, Antibodies, Neoplasm/immunology, Antibody Specificity, Brain/immunology, Cell Line, Cells, Cultured, Cross Reactions, Dogs, Glioma/immunology, Humans, Melanoma/immunology, Meningioma/immunology, Neoplasms, Experimental/immunology, Neuroblastoma/immunology, Rabbits, Rats
Pubmed
Web of science
Création de la notice
25/04/2013 13:47
Dernière modification de la notice
20/08/2019 15:31
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