Dégénérescence maculaire liée à l'âge exsudative: efficacité et limites des différents traitements [Exudative age-related macular degeneration: efficacy and limits of the different treatments].

Détails

ID Serval
serval:BIB_BC0DFC82B226
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Dégénérescence maculaire liée à l'âge exsudative: efficacité et limites des différents traitements [Exudative age-related macular degeneration: efficacy and limits of the different treatments].
Périodique
Journal Français D'ophtalmologie
Auteur(s)
Polak M.B., Behar-Cohen F.
ISSN
1773-0597 (Electronic)
ISSN-L
0181-5512
Statut éditorial
Publié
Date de publication
2008
Peer-reviewed
Oui
Volume
31
Numéro
5
Pages
537-556
Langue
français
Notes
Publication types: Case Reports ; English Abstract ; Journal ArticlePublication Status: ppublish
Résumé
Ocular neovascularizations are responsible for irreversible loss of vision in various diseases, including age-related macular degeneration. Treatments have changed greatly, and photodynamic therapy with verteporfin has come into common use. However, the visual prognosis remains poor. The recent approval of new antiangiogenic molecules such as ranibizumab and pegaptanib should allow for new therapeutical possibilities. The unapproved ophthalmological use of bevacizumab requires further studies. This paper updates what is known about old and new neovascularization treatments: their mechanism of action, their efficacy, and their toxicity. It reviews the principal clinical studies, and concludes with the recognized recommendations. For the first time, ophthalmologists can hope not only to stabilize loss of vision, but also to improve visual acuity. Complementary treatments can now be tested in associations, concomitantly or not, with the hope of improving visual results.
Mots-clé
Aged, Aging/physiology, Conjunctival Diseases/etiology, Female, Humans, Macular Degeneration/drug therapy, Male, Middle Aged, Neoplasm Invasiveness, Photochemotherapy/methods, Porphyrins/therapeutic use, Visual Acuity
Pubmed
Web of science
Création de la notice
26/08/2013 14:52
Dernière modification de la notice
20/08/2019 15:30
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