Overestimation of subfoveal choroidal thickness by measurement based on horizontally compressed optical coherence tomography images.
Détails
ID Serval
serval:BIB_BBAC7E5BD924
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Overestimation of subfoveal choroidal thickness by measurement based on horizontally compressed optical coherence tomography images.
Périodique
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
ISSN
1435-702X (Electronic)
ISSN-L
0721-832X
Statut éditorial
Publié
Date de publication
04/2013
Peer-reviewed
Oui
Volume
251
Numéro
4
Pages
1091-1096
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
To measure the difference in subfoveal choroidal thickness between 1:1 pixel (horizontally compressed) images and 1:1 micron images in age-related macular degeneration.
This study included 122 eyes from 122 patients diagnosed with age-related macular degeneration. Choroidal thickness was measured using enhanced-depth imaging optical coherence tomography. The measurement line was drawn as a perpendicular line between Bruch's membrane and the chorio-scleral interface. The thickness was compared between measurements based on a 1:1 pixel image and a 1:1 micron image. Eyes with a straight vertical measurement line and oblique measurement line were classified into vertical measurement group and oblique measurement group, respectively. Intra-group comparisons of subfoveal choroidal thickness measurements based on the 1:1 pixel images and the 1:1 micron images were performed for the two groups.
The mean subfoveal choroidal thicknesses measured on the 1:1 pixel images and the 1:1 micron images were 232.3 ± 106.4 μm and 228.9 ± 108.1 μm, respectively (p = 0.003). In the vertical measurement group (86 eyes), the mean subfoveal choroidal thickness was 226.3 ± 109.9 μm and 225.4 ± 112.0 μm, respectively (p = 0.423). In the oblique measurement group (36 eyes), the thickness was 246.5 ± 97.3 μm and 237.5 ± 98.9 μm, respectively (p < 0.001).
Significant overestimation of the subfoveal choroidal thickness was noted when it was measured on a 1:1 pixel image. This finding suggests that the measurement of choroidal thickness should be performed based on a 1:1 micron image, especially if the measurement line is not vertical.
This study included 122 eyes from 122 patients diagnosed with age-related macular degeneration. Choroidal thickness was measured using enhanced-depth imaging optical coherence tomography. The measurement line was drawn as a perpendicular line between Bruch's membrane and the chorio-scleral interface. The thickness was compared between measurements based on a 1:1 pixel image and a 1:1 micron image. Eyes with a straight vertical measurement line and oblique measurement line were classified into vertical measurement group and oblique measurement group, respectively. Intra-group comparisons of subfoveal choroidal thickness measurements based on the 1:1 pixel images and the 1:1 micron images were performed for the two groups.
The mean subfoveal choroidal thicknesses measured on the 1:1 pixel images and the 1:1 micron images were 232.3 ± 106.4 μm and 228.9 ± 108.1 μm, respectively (p = 0.003). In the vertical measurement group (86 eyes), the mean subfoveal choroidal thickness was 226.3 ± 109.9 μm and 225.4 ± 112.0 μm, respectively (p = 0.423). In the oblique measurement group (36 eyes), the thickness was 246.5 ± 97.3 μm and 237.5 ± 98.9 μm, respectively (p < 0.001).
Significant overestimation of the subfoveal choroidal thickness was noted when it was measured on a 1:1 pixel image. This finding suggests that the measurement of choroidal thickness should be performed based on a 1:1 micron image, especially if the measurement line is not vertical.
Mots-clé
Aged, Aged, 80 and over, Angiogenesis Inhibitors/therapeutic use, Choroid/pathology, Choroid Diseases/diagnosis, Choroid Diseases/drug therapy, Data Compression, Fovea Centralis, Humans, Image Processing, Computer-Assisted, Intravitreal Injections, Middle Aged, Organ Size, Photochemotherapy, Polyps/diagnosis, Polyps/drug therapy, Tomography, Optical Coherence, Vascular Endothelial Growth Factor A/antagonists & inhibitors, Wet Macular Degeneration/diagnosis, Wet Macular Degeneration/drug therapy
Pubmed
Web of science
Création de la notice
10/03/2022 9:04
Dernière modification de la notice
11/03/2022 6:33