Structure of simian virus 40 at 3.8-A resolution

Détails

ID Serval
serval:BIB_B9C233AC4B01
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Structure of simian virus 40 at 3.8-A resolution
Périodique
Nature
Auteur(s)
Liddington  R. C., Yan  Y., Moulai  J., Sahli  R., Benjamin  T. L., Harrison  S. C.
ISSN
0028-0836 (Print)
Statut éditorial
Publié
Date de publication
11/1991
Volume
354
Numéro
6351
Pages
278-84
Notes
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S. --- Old month value: Nov 28
Résumé
The crystallographically determined structure of simian virus 40 shows that the 72 pentamers of viral protein VP1, which form the outer shell, have identical conformations except for the C-terminal arms of their subunits. Five arms emerge from each pentamer and insert into neighbouring pentamers. This tying together of standard building blocks allows for the required variability in packing geometry without sacrificing specificity.
Mots-clé
Amino Acid Sequence Calcium-Binding Proteins/ultrastructure Capsid/*ultrastructure *Capsid Proteins Computer Graphics Crystallography Disulfides/chemistry Humans Macromolecular Substances Models, Molecular Molecular Sequence Data Morphogenesis Protein Conformation Sequence Alignment Simian virus 40/*ultrastructure Virion/ultrastructure X-Ray Diffraction
Pubmed
Web of science
Création de la notice
24/01/2008 20:51
Dernière modification de la notice
20/08/2019 15:27
Données d'usage