Diagnostic performance of Fluorine-18-Fluorodeoxyglucose positron emission tomography for the diagnosis of osteomyelitis related to diabetic foot: a systematic review and a meta-analysis.

Détails

ID Serval
serval:BIB_B91198B49D2A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Diagnostic performance of Fluorine-18-Fluorodeoxyglucose positron emission tomography for the diagnosis of osteomyelitis related to diabetic foot: a systematic review and a meta-analysis.
Périodique
Foot
Auteur⸱e⸱s
Treglia G., Sadeghi R., Annunziata S., Zakavi S.R., Caldarella C., Muoio B., Bertagna F., Ceriani L., Giovanella L.
ISSN
1532-2963 (Electronic)
ISSN-L
0958-2592
Statut éditorial
Publié
Date de publication
12/2013
Peer-reviewed
Oui
Volume
23
Numéro
4
Pages
140-148
Langue
anglais
Notes
Publication types: Journal Article ; Meta-Analysis ; Review
Publication Status: ppublish
Résumé
To systematically review and meta-analyse published data about the diagnostic performance of Fluorine-18-Fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET) and PET/computed tomography (PET/CT) in osteomyelitis related to diabetic foot.
A comprehensive literature search of studies on (18)F-FDG-PET and PET/CT in patients with diabetic foot was performed. Pooled sensitivity, specificity, positive and negative likelihood ratio (LR+ and LR-) and diagnostic odds ratio (DOR) and area under the summary ROC curve of (18)F-FDG-PET and PET/CT in patients with osteomyelitis related to diabetic foot were calculated.
Nine studies comprising 299 patients with diabetic foot were included in the qualitative analysis (systematic review) and discussed. The quantitative analysis (meta-analysis) of four selected studies provided the following results on a per patient-based analysis: sensitivity was 74% [95% confidence interval (95%CI): 60-85%], specificity 91% (95%CI: 85-96%), LR+ 5.56 (95%CI: 2.02-15.27), LR- 0.37 (95%CI: 0.10-1.35), and DOR 16.96 (95%CI: 2.06-139.66). The area under the summary ROC curve was 0.874.
In patients with suspected osteomyelitis related to diabetic foot (18)F-FDG-PET and PET/CT demonstrated a high specificity, being potentially useful tools if combined with other imaging methods such as MRI. Nevertheless, the literature focusing on the use of (18)F-FDG-PET and PET/CT in this setting remains still limited.

Mots-clé
Diabetic Foot/diagnostic imaging, Fluorodeoxyglucose F18, Humans, Multimodal Imaging, Osteomyelitis/diagnostic imaging, Positron-Emission Tomography, Radiopharmaceuticals, Sensitivity and Specificity, Tomography, X-Ray Computed, (18)F-FDG, Diabetic foot, Osteomyelitis, PET/CT, Positron emission tomography
Pubmed
Création de la notice
20/08/2017 19:17
Dernière modification de la notice
20/08/2019 15:27
Données d'usage