Anomalies du transport rénal du sodium et sensibilité au sel de la pression artérielle [Abnormalities of renal sodium transport and blood pressure sensitivity to salt].

Détails

ID Serval
serval:BIB_B8DE0612E09D
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Anomalies du transport rénal du sodium et sensibilité au sel de la pression artérielle [Abnormalities of renal sodium transport and blood pressure sensitivity to salt].
Périodique
Néphrologie et Thérapeutique
Auteur⸱e⸱s
Burnier M.
ISSN
1769-7255 (Print)
ISSN-L
1769-7255
Statut éditorial
Publié
Date de publication
2007
Peer-reviewed
Oui
Volume
3 Suppl 2
Numéro
Suppl. 2
Pages
S94-S98
Langue
français
Notes
Publication types: English Abstract ; Journal Article
Publication Status: ppublish
Résumé
The blood pressure response to changes in dietary salt intake is highly variable among individuals and this heterogeneity results from the combined effects of genetic and environmental factors. In recent years, considerable progress has been made in our understanding of the pathogenic mechanisms leading to the development of salt-sensitive hypertension. Much information has come from the investigation of rare monogenic forms of salt-sensitive hypertension and has focused the attention on alterations of renal sodium handling occurring essentially in the distal segments of the nephron. There is now also extending experimental, clinical, genetic and epidemiological evidence suggesting that proximal tubular function is an important determinant of the blood pressure response to salt that would deserve a greater attention.
Mots-clé
Biological Transport, Blood Pressure/drug effects, Blood Pressure/physiology, Humans, Hypertension/etiology, Hypertension/physiopathology, Kidney/physiology, Kidney Tubules, Proximal/physiology, Kidney Tubules, Proximal/physiopathology, Sodium/physiology, Sodium, Dietary/adverse effects
Pubmed
Web of science
Création de la notice
06/03/2008 11:33
Dernière modification de la notice
20/08/2019 15:26
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