Admixture mapping of quantitative traits in Populus hybrid zones: power and limitations.

Détails

ID Serval
serval:BIB_B84F204D7F0B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Admixture mapping of quantitative traits in Populus hybrid zones: power and limitations.
Périodique
Heredity
Auteur⸱e⸱s
Lindtke D., González-Martínez S.C., Macaya-Sanz D., Lexer C.
ISSN
1365-2540 (Electronic)
ISSN-L
0018-067X
Statut éditorial
Publié
Date de publication
2013
Volume
111
Numéro
6
Pages
474-485
Langue
anglais
Résumé
Uncovering the genetic architecture of species differences is of central importance for understanding the origin and maintenance of biological diversity. Admixture mapping can be used to identify the number and effect sizes of genes that contribute to the divergence of ecologically important traits, even in taxa that are not amenable to laboratory crosses because of their long generation time or other limitations. Here, we apply admixture mapping to naturally occurring hybrids between two ecologically divergent Populus species. We map quantitative trait loci for eight leaf morphological traits using 77 mapped microsatellite markers from all 19 chromosomes of Populus. We apply multivariate linear regression analysis allowing the modeling of additive and non-additive gene action and identify several candidate genomic regions associated with leaf morphology using an information-theoretic approach. We perform simulation studies to assess the power and limitations of admixture mapping of quantitative traits in natural hybrid populations for a variety of genetic architectures and modes of gene action. Our results indicate that (1) admixture mapping has considerable power to identify the genetic architecture of species differences if sample sizes and marker densities are sufficiently high, (2) modeling of non-additive gene action can help to elucidate the discrepancy between genotype and phenotype sometimes seen in interspecific hybrids, and (3) the genetic architecture of leaf morphological traits in the studied Populus species involves complementary and overdominant gene action, providing the basis for rapid adaptation of these ecologically important forest trees.
Mots-clé
Chromosome Mapping/methods, Chromosomes, Plant/genetics, Genetic Linkage, Genotype, Microsatellite Repeats, Populus/classification, Populus/genetics, Quantitative Trait Loci
Pubmed
Web of science
Open Access
Oui
Création de la notice
30/09/2013 9:05
Dernière modification de la notice
20/08/2019 15:26
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