Uterine contractility during the menstrual cycle

Détails

ID Serval
serval:BIB_B796EB9EC231
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Uterine contractility during the menstrual cycle
Périodique
Human Reproduction
Auteur(s)
Bulletti  C., de Ziegler  D., Polli  V., Diotallevi  L., Del Ferro  E., Flamigni  C.
ISSN
0268-1161
Statut éditorial
Publié
Date de publication
06/2000
Peer-reviewed
Oui
Volume
15 Suppl 1
Pages
81-9
Notes
Comparative Study
Evaluation Studies
Journal Article --- Old month value: Jun
Résumé
The non-pregnant uterus shows different patterns of contractility during the menstrual cycle. A renewed interest in uterine contractility has resulted from reports of non-invasive ultrasound (US) based studies. To clarify the changes in uterine contractility occurring throughout the menstrual cycle, we prospectively studied uterine contractions (UC) at six representative stages with US and intrauterine pressure (IUP) based approaches in 30 cycling volunteers. Results showed UC frequency could be measured by either US or IUP. UC amplitude and resting pressure tone could only be assessed by IUP. Conversely, direction of UC displacement could only be assessed by US. UC frequency increased at mid-cycle and decreased throughout the luteal phase suggesting oestradiol and progesterone exert positive and negative actions on uterine contractility, respectively. UC amplitude increased throughout the menstrual cycle to maximum values in the late luteal phase. Retrograde UC were most frequent at mid-cycle and convergent ('opposing') UC predominated during the luteal phase. While the former pattern ensures sperm transport, the latter may facilitate embryo implantation. In conclusion, UC changes throughout the menstrual cycle assessed by US and IUP emphasize the hormonal dependence of uterine contractility. Although UC patterns favouring sperm transport appear regulated by oestradiol, uterine quiescence and the dominance of convergent UC prevailing at the time of implantation are linked to progesterone. These data will serve to identify and treat possible dyskinetic changes in uterine contractility, particularly in women suffering from infertility, endometriosis, and dysmenorrhea.
Mots-clé
Adult Female Humans Menstrual Cycle/*physiology Pressure Reference Values Ultrasonography/methods *Uterine Contraction
Pubmed
Web of science
Création de la notice
28/02/2008 11:37
Dernière modification de la notice
20/08/2019 15:25
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