Elevated and similar urinary testosterone/epitestosterone ratio in all samples of a competition testing: Suspicion of a manipulation

Détails

ID Serval
serval:BIB_B63895AC54DA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Elevated and similar urinary testosterone/epitestosterone ratio in all samples of a competition testing: Suspicion of a manipulation
Périodique
Forensic Science International
Auteur⸱e⸱s
Robinson  N., Castella  V., Saudan  C., Sottas  P. E., Schweizer  C., Dimo-Simonin  N., Mangin  P., Saugy  M.
ISSN
0379-0738
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
163
Numéro
1-2
Pages
148-151
Résumé
The case of seven urine samples collected for anti-doping purposes during a cycling stage race With moderately elevated testosterone and epitestosterone ratio (T/E) is reported. The very low probability of having all seven urine samples with such similar elevated T/E ratio (from 3.2 to 4.7) was very suspicious. Different pattern classification tools were tested to categorize the most similar steroid profiles, but none of the models enabled a clear classification of the different urine samples. Subsequently, genetic profiling of all urine samples was performed and demonstrated that three of the seven samples were collected from the same cyclist. Finally, the International Federation confirmed DNA profiling results. This suggests that urinary steroid data using several methodologies are not appropriate for identification purposes and to an extent not unique to individuals.
Pubmed
Web of science
Création de la notice
08/02/2008 17:43
Dernière modification de la notice
20/08/2019 15:24
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