Sodium intake and blood pressure in children and adolescents: protocol for a systematic review and meta-analysis.

Détails

Ressource 1Télécharger: BIB_B4EEC8F74AC8.pdf (609.31 [Ko])
Etat: Public
Version: Final published version
ID Serval
serval:BIB_B4EEC8F74AC8
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Sodium intake and blood pressure in children and adolescents: protocol for a systematic review and meta-analysis.
Périodique
BMJ open
Auteur⸱e⸱s
Leyvraz M., Taffé P., Chatelan A., Paradis G., Tabin R., Bovet P., Bochud M., Chiolero A.
ISSN
2044-6055 (Electronic)
ISSN-L
2044-6055
Statut éditorial
Publié
Date de publication
21/09/2016
Peer-reviewed
Oui
Volume
6
Numéro
9
Pages
e012518
Langue
anglais
Notes
Publication types: ARTICLE
Publication Status: epublish
Publication types: Journal Article

Résumé
Hypertension is a major risk factor for cardiovascular diseases. In adults, high sodium intake is associated with elevated blood pressure. In children, experimental studies have shown that reducing sodium intake can reduce blood pressure. However, their external validity is limited, notably because the sodium reduction was substantial and not applicable in a real-life setting. Observational studies, on the other hand, allow assess the association between blood pressure and sodium intake across usual levels of consumption. There is also evidence that the association differs between subgroups of children according to age and body weight. Our objective is to conduct a systematic review and meta-analysis of experimental and observational studies on the association between sodium intake and blood pressure in children and adolescents and to assess whether the association differs according to age and body weight.
A systematic search of the MEDLINE, EMBASE, CINAHL and CENTRAL databases will be conducted and supplemented by a manual search of bibliographies and unpublished studies. Experimental and observational studies involving children or adolescents between 0 and 18 years of age will be included. The exposure will be dietary sodium intake, estimated using different methods including urinary sodium excretion. The outcomes will be systolic and diastolic blood pressure, elevated blood pressure and hypertension. If appropriate, meta-analyses will be performed by pooling data across all studies together and separately for experimental and observational studies. Subgroup meta-analyses by age and body weight will be also conducted. Moreover, separate meta-analyses for different sodium intake levels will be conducted to investigate the dose-response relationship.
This systematic review and meta-analysis will be published in a peer-reviewed journal. A report will be prepared for national authorities and other stakeholders in the domains of nutrition, public health, and child health in Switzerland.
CRD42016038245.

Pubmed
Web of science
Open Access
Oui
Création de la notice
29/09/2016 18:43
Dernière modification de la notice
20/08/2019 15:23
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