Modulations of human autonomic function induced by positive pressure-assisted breathing.

Détails

ID Serval
serval:BIB_B4C0E160B17D
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Modulations of human autonomic function induced by positive pressure-assisted breathing.
Périodique
Clinical Physiology and Functional Imaging
Auteur(s)
Garet M., Barthélémy J.C., Degache F., Pichot V., Duverney D., Roche F.
ISSN
1475-0961 (Print)
ISSN-L
1475-0961
Statut éditorial
Publié
Date de publication
2006
Peer-reviewed
Oui
Volume
26
Numéro
1
Pages
15-20
Langue
anglais
Résumé
In order to examine the acute autonomic response in humans during and immediately after positive pressure-assisted (PPA) breathing, spontaneous cardiac baroreflex (BR) sensitivity was studied through the adaptation of consecutive RR intervals in response to spontaneous systolic blood pressure fluctuations in 11 healthy subjects. The gain (alpha-index) in baroreceptor reflex was estimated using cross-spectral analysis (RR interval variability and systolic blood pressure variability) for the low frequency (LF) and high frequency (HF) bands. All measurements were made under fixed breathing rate (12 breaths per minute), and realized consecutively at baseline level (20 min), after-short inspiratory pressure support plus positive end-expiratory airway pressure (IPS + PEEP) ventilation (15 min), again under normal conditions (20 min; recovery period) and, finally, during a standard upward orthostatic challenge test (15 min; orthostatic challenge). The spontaneous BR gain in the HF band increases slightly during ventilation (+26.1 +/- 11.7%, P<0.05) and decreases significantly during recovery without any significant alteration in mean heart rate, systolic or diastolic blood pressure. The spontaneous BR gain in the LF band decreases during IPS + PEEP ventilation (8.4 +/- 4.4 versus 12.7 +/- 6.2 ms mm(-1) Hg; P<0.05) and returns to basal level during recovery. Orthostatic challenge altered significantly the BR gain in both HF and LF bands with significant heart rate acceleration. In humans, while the parasympathetic control of heart rate and blood pressure is found moderately enhanced, the sympathetic BR drive appears significantly and transitory altered under short term IPS + PEEP ventilation with a degree of alteration comparable to those observed during orthostatic challenge.
Mots-clé
Adult, Autonomic Nervous System/physiology, Baroreflex/physiology, Blood Pressure/physiology, Electrocardiography, Female, Heart Rate/physiology, Humans, Male, Positive-Pressure Respiration
Pubmed
Web of science
Création de la notice
19/10/2010 16:22
Dernière modification de la notice
20/08/2019 15:23
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