Expectancy and belief modulate the neuronal substrates of pain treated by acupuncture.

Détails

ID Serval
serval:BIB_B0E84C3BBA59
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Expectancy and belief modulate the neuronal substrates of pain treated by acupuncture.
Périodique
Neuroimage
Auteur⸱e⸱s
Pariente J., White P., Frackowiak R.S., Lewith G.
ISSN
1053-8119 (Print)
ISSN-L
1053-8119
Statut éditorial
Publié
Date de publication
2005
Volume
25
Numéro
4
Pages
1161-1167
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Both specific and non-specific factors may play a role in acupuncture therapy for pain. We explored the cerebral consequences of needling and expectation with real acupuncture, placebo acupuncture and skin-prick, using a single-blind, randomized crossover design with 14 patients suffering from painful osteoarthritis, who were scanned with positron emission tomography (PET). The three interventions, all of which were sub-optimal acupuncture treatment, did not modify the patient's pain. The insula ipsilateral to the site of needling was activated to a greater extent during real acupuncture than during the placebo intervention. Real acupuncture and placebo (with the same expectation of effect as real acupuncture) caused greater activation than skin prick (no expectation of a therapeutic effect) in the right dorsolateral prefrontal cortex, anterior cingulate cortex, and midbrain. These results suggest that real acupuncture has a specific physiological effect and that patients' expectation and belief regarding a potentially beneficial treatment modulate activity in component areas of the reward system.
Mots-clé
Acupuncture, Attitude, Brain Mapping, Female, Functional Laterality/physiology, Humans, Male, Middle Aged, Pain/psychology, Pain/radionuclide imaging, Physical Stimulation, Placebo Effect, Placebos, Positron-Emission Tomography, Questionnaires, Reward, Single-Blind Method, Skin/innervation
Pubmed
Web of science
Création de la notice
11/09/2011 18:23
Dernière modification de la notice
20/08/2019 15:19
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