Insuffisance renale chronique et medicaments antidiabetiques. [Chronic kidney disease and antidiabetic treatment]

Détails

ID Serval
serval:BIB_AF44B6D9AFE2
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Insuffisance renale chronique et medicaments antidiabetiques. [Chronic kidney disease and antidiabetic treatment]
Périodique
Revue Médicale Suisse
Auteur(s)
Berwert  L., Teta  D., Zanchi  A.
ISSN
1660-9379
Statut éditorial
Publié
Date de publication
03/2007
Volume
3
Numéro
101
Pages
598-604
Notes
Case Reports
English Abstract
Journal Article
Review --- Old month value: Mar 7
Résumé
Diabetic nephropathy is the leading cause of chronic renal failure (CRF) in Europe. About fifty percent of diabetic subjects develop microalbuminuria, which progresses towards established diabetic nephropathy in one third of patients. The treatment of type 2 diabetes in a patient with CRF is a challenge for the general practitioner, because of the accumulation of drugs and/or specific metabolites. Sulfonylureas are associated with an increased risk of hypoglycaemia. Biguanides may exceptionally cause life-threatening lactic acidosis. Glitazones have an interesting profile since they decrease microalbuminuria and blood pressure. However, their safety is not well defined in the context of CRF In the case of severe CRF, only insulin and repaglinide can be recommended.
Mots-clé
Biguanides/therapeutic use Diabetes Mellitus, Type 2/*complications/*drug therapy Diabetic Nephropathies/*etiology Female Humans Kidney Failure, Chronic/*etiology Middle Aged Sulfonylurea Compounds/therapeutic use Thiazolidinediones/therapeutic use
Pubmed
Création de la notice
11/02/2008 10:30
Dernière modification de la notice
20/08/2019 16:18
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