Chronic hand eczema: A prospective analysis of the Swiss CARPE registry focusing on factors associated with clinical and quality of life improvement.
Détails
ID Serval
serval:BIB_AEE8010EFA16
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Chronic hand eczema: A prospective analysis of the Swiss CARPE registry focusing on factors associated with clinical and quality of life improvement.
Périodique
Contact dermatitis
ISSN
1600-0536 (Electronic)
ISSN-L
0105-1873
Statut éditorial
Publié
Date de publication
09/2018
Peer-reviewed
Oui
Volume
79
Numéro
3
Pages
136-148
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Hand eczema (HE) is common and may follow a chronic disease course. So far, prospective studies investigating the risk factors for disease progression as a prerequisite for targeted prevention are scarce.
To evaluate the overall association of HE-associated factors with clinical and quality of life (QoL) improvement during a follow-up of 2 years.
Data of the prospective patient cohort (N = 199) followed by the Swiss chronic HE (CHE) registry on long-term patient management (CARPE-CH) were analysed by means of both classic regression and semantic map analyses.
Both severity of HE and QoL significantly improved over the period of 2 years (P < .001). However, 20% of patients had moderate to severe HE after 2 years of follow-up. As factors associated with an unfavourable CHE clinical course and QoL, environmental exposures, male sex, occupational skin disease, job loss or change at baseline, allergic contact dermatitis, a chronic disease course, palmar localization and widespread eczema were identified.
Analysis of prospective data from CARPE-CH shows a complex pattern of associations among variables as shown by semantic map and classic statistical analyses. Factors related to occupational exposure had the highest impact on CHE.
To evaluate the overall association of HE-associated factors with clinical and quality of life (QoL) improvement during a follow-up of 2 years.
Data of the prospective patient cohort (N = 199) followed by the Swiss chronic HE (CHE) registry on long-term patient management (CARPE-CH) were analysed by means of both classic regression and semantic map analyses.
Both severity of HE and QoL significantly improved over the period of 2 years (P < .001). However, 20% of patients had moderate to severe HE after 2 years of follow-up. As factors associated with an unfavourable CHE clinical course and QoL, environmental exposures, male sex, occupational skin disease, job loss or change at baseline, allergic contact dermatitis, a chronic disease course, palmar localization and widespread eczema were identified.
Analysis of prospective data from CARPE-CH shows a complex pattern of associations among variables as shown by semantic map and classic statistical analyses. Factors related to occupational exposure had the highest impact on CHE.
Mots-clé
Chronic Disease/epidemiology, Dermatitis, Occupational/epidemiology, Eczema/epidemiology, Hand Dermatoses/epidemiology, Humans, Occupational Exposure/statistics & numerical data, Prospective Studies, Quality of Life, Registries, Severity of Illness Index, Switzerland/epidemiology, CARPE, chronic hand eczema, clinical improvement, epidemiology, follow-up, quality of life, semantic map analysis
Pubmed
Web of science
Création de la notice
29/06/2018 17:26
Dernière modification de la notice
20/08/2019 16:18
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