Drinking patterns of alcohol and risk of major adverse cardiovascular events after an acute coronary syndrome.
Détails
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_AEB6B2CEB3BE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Drinking patterns of alcohol and risk of major adverse cardiovascular events after an acute coronary syndrome.
Périodique
European journal of preventive cardiology
ISSN
2047-4881 (Electronic)
ISSN-L
2047-4873
Statut éditorial
Publié
Date de publication
11/05/2024
Peer-reviewed
Oui
Volume
31
Numéro
7
Pages
845-855
Langue
anglais
Notes
Publication types: Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
To evaluate the risk of alcohol consumption after acute coronary syndromes (ACS).
A total of 6557 patients hospitalized for ACS at four Swiss centres were followed over 12 months. Weekly alcohol consumption was collected at baseline and 12 months. Binge drinking was defined as consumption of ≥6 units of alcohol on one occasion. Major adverse cardiovascular events (MACE) were defined as a composite of cardiac death, myocardial infarction, stroke, or clinically indicated target vessel coronary revascularization. Cox regression analysis was performed to assess the risk of MACE in patients with heavy (>14 standard units/week), moderate (7-14 standard units per week), light consumption (<1 standard unit/week), or abstinence, and with binge drinking episodes, adjusted for baseline differences. At baseline, 817 (13.4%) patients reported heavy weekly alcohol consumption. At 1-year follow-up, 695/1667 (41.6%) patients reported having at least one or more episodes of binge drinking per month. The risk for MACE was not significantly higher in those with heavy weekly consumption compared to abstinence [8.6% vs. 10.2%, hazard ratio (HR) 0.97, 95% confidence interval (CI) 0.69-1.36] or light consumption (8.6% vs. 8.5%, HR 1.41, 95% CI 0.97-2.06). Compared to patients with no binge drinking, the risk of MACE was dose-dependently higher in those with binge drinking with less than one episode per month (9.2% vs. 7.8%, HR 1.61, 95% CI 1.23-2.11) or one or more episodes per month (13.6% vs. 7.8%, HR 2.17, 95% CI 1.66-2.83).
Binge drinking during the year following an ACS, even less than once per month, is associated with worse clinical outcomes.
A total of 6557 patients hospitalized for ACS at four Swiss centres were followed over 12 months. Weekly alcohol consumption was collected at baseline and 12 months. Binge drinking was defined as consumption of ≥6 units of alcohol on one occasion. Major adverse cardiovascular events (MACE) were defined as a composite of cardiac death, myocardial infarction, stroke, or clinically indicated target vessel coronary revascularization. Cox regression analysis was performed to assess the risk of MACE in patients with heavy (>14 standard units/week), moderate (7-14 standard units per week), light consumption (<1 standard unit/week), or abstinence, and with binge drinking episodes, adjusted for baseline differences. At baseline, 817 (13.4%) patients reported heavy weekly alcohol consumption. At 1-year follow-up, 695/1667 (41.6%) patients reported having at least one or more episodes of binge drinking per month. The risk for MACE was not significantly higher in those with heavy weekly consumption compared to abstinence [8.6% vs. 10.2%, hazard ratio (HR) 0.97, 95% confidence interval (CI) 0.69-1.36] or light consumption (8.6% vs. 8.5%, HR 1.41, 95% CI 0.97-2.06). Compared to patients with no binge drinking, the risk of MACE was dose-dependently higher in those with binge drinking with less than one episode per month (9.2% vs. 7.8%, HR 1.61, 95% CI 1.23-2.11) or one or more episodes per month (13.6% vs. 7.8%, HR 2.17, 95% CI 1.66-2.83).
Binge drinking during the year following an ACS, even less than once per month, is associated with worse clinical outcomes.
Mots-clé
Humans, Acute Coronary Syndrome/mortality, Acute Coronary Syndrome/epidemiology, Male, Female, Middle Aged, Aged, Switzerland/epidemiology, Risk Factors, Time Factors, Alcohol Drinking/adverse effects, Alcohol Drinking/epidemiology, Binge Drinking/epidemiology, Binge Drinking/complications, Risk Assessment, Proportional Hazards Models, Alcohol Abstinence, Prognosis, Myocardial Infarction/epidemiology, Myocardial Infarction/mortality, Prospective Studies, Stroke/epidemiology, Stroke/mortality, Stroke/etiology, Acute coronary syndromes, Alcohol consumption, Binge drinking, Cardiovascular prevention, Lifestyle, Secondary cardiovascular prevention
Pubmed
Web of science
Open Access
Oui
Création de la notice
28/11/2023 9:56
Dernière modification de la notice
14/05/2024 9:21