Testostérone et os: indications et limites [Testosterone and bone: indications and limitations].
Détails
ID Serval
serval:BIB_AD55A62BC2C9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Testostérone et os: indications et limites [Testosterone and bone: indications and limitations].
Périodique
Revue Médicale Suisse
ISSN
1660-9379 (Print)
ISSN-L
1660-9379
Statut éditorial
Publié
Date de publication
2011
Volume
7
Numéro
299
Pages
1311-1315
Langue
français
Notes
Publication types: English Abstract ; Journal ArticlePublication Status: ppublish
Résumé
Osteoporosis incidence increases exponentially with age in men and hypogonadism represents a risk factor. Sex steroids levels are correlated to bone mineral density and to fracture prevalence. Most studies demonstrate an improvement in bone mineral density in men with hypogonadism as a result of testosterone therapy. Nevertheless there are no data evaluating the effect of testosterone therapy on fractures in men. Approximately 20% of men older than 60 have a total testosterone level lower than the lower limit of the reference range but there is no true consensus on the definition of hypogonadism in older men. In older men we recommend to treat only if total morning testosterone levels are < 8 nmol/l or even < 6,9 nmol/l on several occasions in the absence of any reversible illness and if there is no contraindication for treatment.
Mots-clé
Androgens/pharmacology, Androgens/therapeutic use, Bone Density/drug effects, Humans, Hypogonadism/complications, Hypogonadism/drug therapy, Male, Osteoporosis/complications, Osteoporosis/etiology, Osteoporotic Fractures/etiology, Osteoporotic Fractures/prevention & control, Risk Factors, Testosterone/pharmacology, Testosterone/therapeutic use, Treatment Outcome
Pubmed
Création de la notice
16/11/2011 12:38
Dernière modification de la notice
20/08/2019 16:17