Food safety in solid-organ transplant recipients: a single-center qualitative study
Détails
Etat: Public
Version: Après imprimatur
Licence: Non spécifiée
ID Serval
serval:BIB_ACE889B287A6
Type
Mémoire
Sous-type
(Mémoire de) maîtrise (master)
Collection
Publications
Institution
Titre
Food safety in solid-organ transplant recipients: a single-center qualitative study
Directeur⸱rice⸱s
MANUEL O.
Codirecteur⸱rice⸱s
MOMBELLI M.
Détails de l'institution
Université de Lausanne, Faculté de biologie et médecine
Statut éditorial
Acceptée
Date de publication
2018
Langue
anglais
Nombre de pages
32
Résumé
Infections represent an important source of morbidity and mortality in solid organ
transplant recipients due to the state of immunosuppression associated with the use
of anti-rejection treatments. Infection control and eviction of exposure risks is an
important strategy for post-transplant management in these patients. Food-borne
pathogens are one source of disease which is commonly targeted by strict guidelines
on food avoidance and behaviors to adopt in order to minimize the risk of infection.
However, these guidelines are not evidence-based, but are rather based on common
sense, expert opinion, or knowledge of mechanisms of transmission of specific
pathogens. Moreover, adherence of transplant patients to these guidelines is largely
unexplored. Thus, it remains unknown if protection strategies are at all effective, or
even if patients apply them in their daily lives.
In this study, we used a self-report survey approach to ask whether 197 transplant
patients treated the University Hospital of Lausanne (CHUV) applied the foodassociated
behaviors prescribed by physicians, and whether sub-populations of
patients could be differentiated by such behaviors. In particular, we asked if guideline
adherence differed between recipients of different organs, or between patients at
different time-points after transplantation, notably in the first year post-transplant or
later. We found that over 90% of patients had consumed risk-associated food (RAF)
on at least one occasion since the transplant, and that 74% reported occasional or
frequent consumption of one or several RAFs. In contrast, hygiene recommendations
were followed in a more reliable manner, with almost 70% reporting following them all
of or most of the time. Finally, a series of hypothetical situations where participants
were again tested on their general knowledge of risks associated with foods and
behaviors to adopt showed that 71% of patients were unable to identify all situations
where risk may be present. In general, higher levels of adherence to guidelines
seemed to be associated with early post transplant period.
In conclusion, transplant recipients frequently consume risk associated food,
particularly late after transplantation and they follow appropriate measures of food
hygiene. Whether this behavior is associated with increase infection rates needs to be
further investigated.
transplant recipients due to the state of immunosuppression associated with the use
of anti-rejection treatments. Infection control and eviction of exposure risks is an
important strategy for post-transplant management in these patients. Food-borne
pathogens are one source of disease which is commonly targeted by strict guidelines
on food avoidance and behaviors to adopt in order to minimize the risk of infection.
However, these guidelines are not evidence-based, but are rather based on common
sense, expert opinion, or knowledge of mechanisms of transmission of specific
pathogens. Moreover, adherence of transplant patients to these guidelines is largely
unexplored. Thus, it remains unknown if protection strategies are at all effective, or
even if patients apply them in their daily lives.
In this study, we used a self-report survey approach to ask whether 197 transplant
patients treated the University Hospital of Lausanne (CHUV) applied the foodassociated
behaviors prescribed by physicians, and whether sub-populations of
patients could be differentiated by such behaviors. In particular, we asked if guideline
adherence differed between recipients of different organs, or between patients at
different time-points after transplantation, notably in the first year post-transplant or
later. We found that over 90% of patients had consumed risk-associated food (RAF)
on at least one occasion since the transplant, and that 74% reported occasional or
frequent consumption of one or several RAFs. In contrast, hygiene recommendations
were followed in a more reliable manner, with almost 70% reporting following them all
of or most of the time. Finally, a series of hypothetical situations where participants
were again tested on their general knowledge of risks associated with foods and
behaviors to adopt showed that 71% of patients were unable to identify all situations
where risk may be present. In general, higher levels of adherence to guidelines
seemed to be associated with early post transplant period.
In conclusion, transplant recipients frequently consume risk associated food,
particularly late after transplantation and they follow appropriate measures of food
hygiene. Whether this behavior is associated with increase infection rates needs to be
further investigated.
Création de la notice
03/09/2019 11:28
Dernière modification de la notice
08/09/2020 7:10