When food meets man: the contribution of epigenetics to health.

Détails

ID Serval
serval:BIB_AC0115928608
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
When food meets man: the contribution of epigenetics to health.
Périodique
Nutrients
Auteur(s)
De Fabiani E., Mitro N., Gilardi F., Galmozzi A., Caruso D., Crestani M.
ISSN
2072-6643 (Electronic)
ISSN-L
2072-6643
Statut éditorial
Publié
Date de publication
05/2010
Peer-reviewed
Oui
Volume
2
Numéro
5
Pages
551-571
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
Post-translational modifications of chromatin contribute to the epigenetic control of gene transcription. The response to food intake and individual nutrients also includes epigenetic events. Bile acids are necessary for lipid digestion and absorption, and more recently have emerged as signaling molecules. Their synthesis is transcriptionally regulated also in relation to the fasted-to-fed cycle, and interestingly, the underlying mechanisms include chromatin remodeling at promoters of key genes involved in their metabolism. Several compounds present in nutrients affect gene transcription through epigenetic mechanisms and recent studies demonstrate that, beyond the well known anti-cancer properties, they beneficially affect energy metabolism.
Mots-clé
Bile Acids and Salts/metabolism, Chromatin/metabolism, Chromatin Assembly and Disassembly/genetics, Energy Metabolism/physiology, Epigenesis, Genetic, Histone Deacetylases/metabolism, Humans, Protein Processing, Post-Translational/genetics, bile acid synthesis, cholesterol metabolism, chromatin, fasted-to-fed cycle, gluconeogenesis, histone deacetylases, resveratrol, sirtuins, transcriptional regulation
Pubmed
Web of science
Open Access
Oui
Création de la notice
21/03/2019 12:29
Dernière modification de la notice
20/02/2020 7:26
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