Diffusion Spectrum Imaging after stroke shows structural changes in the contra-lateral motor network correlating with functional recovery
Détails
Etat: Public
Version: de l'auteur⸱e
ID Serval
serval:BIB_AB3EE8C29132
Type
Actes de conférence (partie): contribution originale à la littérature scientifique, publiée à l'occasion de conférences scientifiques, dans un ouvrage de compte-rendu (proceedings), ou dans l'édition spéciale d'un journal reconnu (conference proceedings).
Sous-type
Abstract (résumé de présentation): article court qui reprend les éléments essentiels présentés à l'occasion d'une conférence scientifique dans un poster ou lors d'une intervention orale.
Collection
Publications
Institution
Titre
Diffusion Spectrum Imaging after stroke shows structural changes in the contra-lateral motor network correlating with functional recovery
Titre de la conférence
ISMRM 2011, 19th Annual Meeting of the International Society for Magnetic Resonance in Medicine
Adresse
Montreal, Quebec, Canada, May 7-13, 2011
ISBN
1524-6965
Statut éditorial
Publié
Date de publication
2011
Volume
19
Série
Proceedings of the International Society for Magnetic Resonance in Medicine
Pages
4199
Langue
anglais
Résumé
There is growing interest in understanding the role of
the non-injured contra-lateral hemisphere in stroke
recovery. In the experimental field, histological
evidence has been reported that structural changes occur
in the contra-lateral connectivity and circuits during
stroke recovery. In humans, some recent imaging studies
indicated that contra-lateral sub-cortical pathways and
functional and structural cortical networks are
remodeling, after stroke. Structural changes in the
contra-lateral networks, however, have never been
correlated to clinical recovery in patients. To determine
the importance of the contra-lateral structural changes
in post-stroke recovery, we selected a population of
patients with motor deficits after stroke affecting the
motor cortex and/or sub-cortical motor white matter. We
explored i) the presence of Generalized Fractional
Anisotropy (GFA) changes indicating structural
alterations in the motor network of patientsâeuro?
contra-lateral hemisphere as well as their longitudinal
evolution ii) the correlation of GFA changes with
patientsâeuro? clinical scores, stroke size and demographics
data iii) and a predictive model.
the non-injured contra-lateral hemisphere in stroke
recovery. In the experimental field, histological
evidence has been reported that structural changes occur
in the contra-lateral connectivity and circuits during
stroke recovery. In humans, some recent imaging studies
indicated that contra-lateral sub-cortical pathways and
functional and structural cortical networks are
remodeling, after stroke. Structural changes in the
contra-lateral networks, however, have never been
correlated to clinical recovery in patients. To determine
the importance of the contra-lateral structural changes
in post-stroke recovery, we selected a population of
patients with motor deficits after stroke affecting the
motor cortex and/or sub-cortical motor white matter. We
explored i) the presence of Generalized Fractional
Anisotropy (GFA) changes indicating structural
alterations in the motor network of patientsâeuro?
contra-lateral hemisphere as well as their longitudinal
evolution ii) the correlation of GFA changes with
patientsâeuro? clinical scores, stroke size and demographics
data iii) and a predictive model.
Mots-clé
Diffusion MRI, Stroke, Plasticity, CIBM-AIT
Création de la notice
07/01/2014 9:11
Dernière modification de la notice
20/08/2019 16:15
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