Nosocomial bloodstream infection and clinical sepsis

Détails

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Etat: Public
Version: Final published version
Licence: Non spécifiée
ID Serval
serval:BIB_AA79944481F7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Nosocomial bloodstream infection and clinical sepsis
Périodique
Emerging Infectious Diseases
Auteur⸱e⸱s
Hugonnet S, Sax H, Eggimann P., Touveneau S., Chevrolet J.C., Pittet D.
ISSN
1080-6040
Statut éditorial
Publié
Date de publication
2004
Peer-reviewed
Oui
Volume
10
Numéro
1
Pages
76-81
Langue
anglais
Résumé
Primary bloodstream infection (BSI) is a leading, preventable infectious complication in critically ill patients and has a negative impact on patients' outcome. Surveillance definitions for primary BSI distinguish those that are microbiologically documented from those that are not. The latter is known as clinical sepsis, but information on its epidemiologic importance is limited. We analyzed prospective on-site surveillance data of nosocomial infections in a medical intensive care unit. Of the 113 episodes of primary BSI, 33 (29%) were microbiologically documented. The overall BSI infection rate was 19.8 episodes per 1,000 central-line days (confidence interval [CI] 95%, 16.1 to 23.6); the rate fell to 5.8 (CI 3.8 to 7.8) when only microbiologically documented episodes were considered. Exposure to vascular devices was similar in patients with clinical sepsis and patients with microbiologically documented BSI. We conclude that laboratory-based surveillance alone will underestimate the incidence of primary BSI and thus jeopardize benchmarking.
Mots-clé
Adolescent , Adult , Aged , Aged, 80 and over , Cross Infection/*epidemiology/transmission , Equipment Contamination , Female , Hospital Mortality , Humans , Incidence , Intensive Care Units , Male , Middle Aged , Population Surveillance/methods , Sepsis/epidemiology/transmission , Switzerland/epidemiology
Pubmed
Web of science
Création de la notice
02/02/2009 11:32
Dernière modification de la notice
20/08/2019 15:14
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