Pre-, peri- and neonatal risk factors for autism.

Détails

ID Serval
serval:BIB_AA5D03471DFF
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Pre-, peri- and neonatal risk factors for autism.
Périodique
Acta obstetricia et gynecologica Scandinavica
Auteur(s)
Guinchat V., Thorsen P., Laurent C., Cans C., Bodeau N., Cohen D.
ISSN
1600-0412 (Electronic)
ISSN-L
0001-6349
Statut éditorial
Publié
Date de publication
03/2012
Peer-reviewed
Oui
Volume
91
Numéro
3
Pages
287-300
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Review
Publication Status: ppublish
Résumé
To identify pre-, peri- and neonatal risk factors for pervasive developmental disorders (PDD).
We searched the Medline database through March 2011 for relevant case-control and population-based studies on pre-, peri- and neonatal hazards related to PDD, including autism. We identified 85 studies for this review. Data were extracted systematically and organized according to risk factors related to family history, pregnancy, gestational age, delivery, birth milestones and the neonate's condition at birth.
During the prenatal period, risk factors for PDD were advanced maternal or paternal ages, being firstborn vs. third or later, maternal prenatal medication use and mother's status as foreign born. During the perinatal and neonatal periods, the risk factors for PDD were preterm birth, breech presentation, planned cesarean section, low Apgar scores, hyperbilirubinemia, birth defect and a birthweight small for gestational age. The influence of maternal pre-eclampsia, diabetes, vomiting, infections and stress during pregnancy requires further study in order to determine risk for PDD.
Despite evidence for the association of some pre-, peri- and neonatal risk factors associated with PDD, it remains unclear whether these risks are causal or play a secondary role in shaping clinical expression in individuals with genetic vulnerability. A plausible hypothsesis is that improvements in obstetric and neonatal management have led to an increased rate of survivors with pre-existing brain damage. Given the variety of risk factors, we propose that future studies should investigate combinations of multiple factors, rather than focusing on a single factor.
Mots-clé
Apgar Score, Birth Weight, Child Development Disorders, Pervasive/etiology, Delivery, Obstetric, Female, Humans, Infant, Newborn, Obstetric Labor Complications, Pregnancy, Pregnancy Complications, Risk Factors
Pubmed
Web of science
Création de la notice
15/08/2019 9:20
Dernière modification de la notice
03/09/2019 5:26
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