Cancer risk in nuclear workers occupationally exposed to uranium-emphasis on internal exposure.

Détails

ID Serval
serval:BIB_AA46EB1D2811
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Titre
Cancer risk in nuclear workers occupationally exposed to uranium-emphasis on internal exposure.
Périodique
Health physics
Auteur⸱e⸱s
Guseva Canu Irina, Ellis Elizabeth D., Tirmarche Margot
ISSN
0017-9078 (Print)
ISSN-L
0017-9078
Statut éditorial
Publié
Date de publication
01/2008
Peer-reviewed
Oui
Volume
94
Numéro
1
Pages
1-17
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
Workers involved in the nuclear fuel cycle have a potential for internal exposure to uranium. The present review of epidemiological studies of these workers aims to elucidate the relationship between occupational internal uranium exposure and cancer risk. Eighteen cohort and 5 nested case-control studies published since 1980 are reviewed. Workers occupationally exposed to uranium appear to be at increased risk of mortality from neoplasms of the lung, larynx, and lymphatic and haematopoietic tissue. Currently available evidence for a positive association between internal exposure to uranium and the risk of cancer is limited. The common weaknesses in reviewed studies include low statistical power and inaccurate assessment of internal exposure to uranium. Further investigations should focus on precise assessment of occupational exposure and address the issue of potential confounders.

Mots-clé
Case-Control Studies, Digestive System Neoplasms/etiology, Digestive System Neoplasms/mortality, Dose-Response Relationship, Radiation, Female, Hematologic Neoplasms/etiology, Humans, Kidney Neoplasms/etiology, Kidney Neoplasms/mortality, Lung Neoplasms/etiology, Lung Neoplasms/mortality, Male, Neoplasms, Radiation-Induced/etiology, Neoplasms, Radiation-Induced/mortality, Nuclear Energy, Occupational Exposure/adverse effects, Uranium/adverse effects
Pubmed
Web of science
Création de la notice
12/09/2017 15:25
Dernière modification de la notice
20/08/2019 15:14
Données d'usage