Human cerebral activity with increasing inspiratory force: a study using positron emission tomography.

Détails

ID Serval
serval:BIB_A9C0A34ED41A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Human cerebral activity with increasing inspiratory force: a study using positron emission tomography.
Périodique
Journal of Applied Physiology
Auteur⸱e⸱s
Fink G.R., Corfield D.R., Murphy K., Kobayashi I., Dettmers C., Adams L., Frackowiak R.S., Guz A.
ISSN
8750-7587 (Print)
ISSN-L
0161-7567
Statut éditorial
Publié
Date de publication
1996
Volume
81
Numéro
3
Pages
1295-1305
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
Human cerebral activity with increasing inspiratory force: a study using positron emission tomography. J. Appl. Physiol. 81(3): 1295-1305, 1996.--The major aim of this study was to use positron emission tomography (PET) to assess dose-dependent effects of inspiratory loads on relative regional cerebral blood flow as an indication of neuronal activation and recruitment. Six normal men underwent H2 15O-PET scanning during unloaded breathing and with external inspiratory loads (generating mouth pressures of -5, -10, and -15 cmH2O); positive-pressure ventilation against relaxed respiratory muscles acted as control. During unloaded breathing, the supplementary motor area was significantly activated. With the addition of the smallest load, activations also occurred in the right premotor area and bilaterally in the superolateral motor cortex (MI) in areas previously shown to be activated with deeper breathing. There was little further change in these areas with greater loads. Additional force-related activations occurred in the inferolateral sensorimotor cortex, parietal cortex, and midbrain/hypothalamus. The results suggest that volitionally induced increases in inspiratory muscle force are achieved via a complex integration of neuronal activations in cortical and subcortical regions associated with motor control.
Mots-clé
Adult, Cerebral Cortex/physiology, Cerebral Cortex/radionuclide imaging, Cerebrovascular Circulation/physiology, Electromyography, Humans, Male, Respiration/physiology, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
16/09/2011 18:34
Dernière modification de la notice
20/08/2019 15:13
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