Studies on microperoxisomes. VII. Pigment epithelial cells and other cell types in the retina of rodents

Détails

ID Serval
serval:BIB_A9B21363DBC7
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Studies on microperoxisomes. VII. Pigment epithelial cells and other cell types in the retina of rodents
Périodique
Journal of Cell Biology
Auteur(s)
Leuenberger  P. M., Novikoff  A. B.
ISSN
0021-9525 (Print)
Statut éditorial
Publié
Date de publication
05/1975
Volume
65
Numéro
2
Pages
324-34
Notes
Journal Article
Research Support, U.S. Gov't, P.H.S. --- Old month value: May
Résumé
The pigment epithelial cell of the retina actively participates in two aspects of lipid metabolism: (a) the fatty acid esterification of vitamin A and its storage and transport to the photoreceptors, and (b) the phagocytosis and degradation of the lipoprotein membrane disks shed from the photoreceptor cells. Study of the pigment epithelial cells of adult albino and pigmented rodents has revealed the abundance of an organelle, microperoxisomes, not previously known to exist in this cell type. The metabolism, transport, and storage of lipids are major functions of other cell types which possess large numbers of microperoxisomes associated with a highly developed smooth endoplasmic reticulum. Microperoxisomes were encountered, but relatively rarely, in Muller cells and vascular endothelial cells. A tubular system in photoreceptor terminals is reactive in the cytochemical procedure used to visualize microperoxisomes.
Mots-clé
Animals Endoplasmic Reticulum/ultrastructure Epithelial Cells Epithelium/ultrastructure Guinea Pigs Lipids Mice Microbodies/*ultrastructure Microscopy, Electron Organoids/*ultrastructure Photoreceptors/ultrastructure Pigments, Biological Rabbits Retina/*ultrastructure
Pubmed
Web of science
Open Access
Oui
Création de la notice
25/01/2008 10:49
Dernière modification de la notice
20/08/2019 16:13
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