Numerical analysis of the 3-dimensional aortic root morphology during the cardiac cycle.

Détails

ID Serval
serval:BIB_A7AB2BD283D9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Numerical analysis of the 3-dimensional aortic root morphology during the cardiac cycle.
Périodique
European Journal of Cardio-thoracic Surgery
Auteur⸱e⸱s
Berdajs D., Mosbahi S., Forro Z., Gerber C., Ferrari E., Charbonnier D., von Segesser L.K.
ISSN
1873-734X (Electronic)
ISSN-L
1010-7940
Statut éditorial
Publié
Date de publication
04/2016
Peer-reviewed
Oui
Volume
49
Numéro
4
Pages
1213-1221
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
OBJECTIVES: The aim was to define the 3-dimensional (3D) geometrical changes of the aortic root and to determine the local shear stress profile of aortic root elements during the cardiac cycle.
METHODS: Six sonomicrometric crystals (200 Hz) were implanted into the aortic root of five pigs at the commissures and at the aortic root base (AoB). 3D aortic root deformation including volume, torsion and tilt angle were determined. Geometrical data with measured local flow and pressure conditions was used for computed fluid dynamics modelling of the aortic root.
RESULTS: Compared with end-diastole, the sinotubular junction and AoB have maximal expansion at peak ejection: 16.42 ± 6.36 and 7.60 ± 2.52%, and minimal at isovolaemic relaxation: 2.87 ± 1.62 and 1.85 ± 1.79%. Aortic root tilt and rotation angle were maximal at the end of diastole: 17.7 ± 8.8 and 21.2 ± 2.09°, and decreased to 15.24 ± 8.14 and 18.3 ± 0.1.94° at peak ejection. High shear stress >20 Pa was registered at peak ejection at coaptations, and during diastole at the superior two-thirds of the leaflets and intervalvular triangles (IVTs). The leaflet body, inferior one-third of the IVTs and valve nadir were exposed to moderate shear stress (8-16 Pa) during the cardiac cycle.
CONCLUSIONS: Aortic root geometry demonstrates precise 3D changes of tilt and rotation angle. Reduction of angles during ejection results in a straight cylinder with low shear stress that facilitates the ejection; the increase during diastole results in a tilted frustum with elevated shear stress. Findings can be used for comparative analysis of native and synthetic structures with individual compliance.
Pubmed
Web of science
Open Access
Oui
Création de la notice
23/03/2016 13:14
Dernière modification de la notice
20/08/2019 16:12
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