Modern multimodal neuroimaging for radiosurgery: the example of PET scan integration.

Détails

ID Serval
serval:BIB_A56B1879070B
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Modern multimodal neuroimaging for radiosurgery: the example of PET scan integration.
Périodique
Acta Neurochirurgica. Supplement
Auteur(s)
Levivier M., Massager N., Wikler D., Goldman S.
ISSN
0065-1419 (Print)
ISSN-L
0065-1419
Statut éditorial
Publié
Date de publication
2004
Volume
91
Pages
1-7
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Radiosurgery relies critically on medical imaging modalities. Leksell Gamma Knife (LGK) radiosurgery presents the highest requirements in terms of imaging accuracy as the treatment is applied in a single high-dose session with no other spatial control than medical imaging. The advent of new imaging modalities opens challenges for LGK planning strategies. The integration of stereotactic PET in LGK represents an example of such application of modern multimodality imaging in radiosurgery. Our experience consists of 80 patients treated with the combination of MR/CT and PET guidance. In order to analyze the specific contribution of PET findings, we developed a classification reflecting the strategy used to define the target volume. When combining PET and MR information, 102 target volumes were defined, because some patients presented with multiple lesions or multifocal tumor areas. Abnormal PET uptake was found in 86% of the lesions, and this information altered significantly the MR-defined tumor in 73%. In conclusion, integration of PET in radiosurgery provides additional information opening new perspectives for the treatment of brain tumors. The use of a standardized classification allows to assess the relative role of PET. A similar approach could be useful and may serve as a template for the evaluation of the integration of other new imaging modalities in radiosurgery.
Mots-clé
Adenoma/diagnosis, Adenoma/surgery, Brain/pathology, Brain/surgery, Brain Neoplasms/diagnosis, Brain Neoplasms/secondary, Contrast Media/administration & dosage, Energy Metabolism/physiology, Fluorodeoxyglucose F18/diagnostic use, Gadolinium DTPA/diagnostic use, Humans, Image Enhancement, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Neoplasm Recurrence, Local/diagnosis, Neoplasm Recurrence, Local/surgery, Neuronavigation, Phantoms, Imaging, Pituitary Neoplasms/diagnosis, Pituitary Neoplasms/surgery, Positron-Emission Tomography, Quality Control, Radiosurgery, Sensitivity and Specificity, Tomography, X-Ray Computed
Pubmed
Création de la notice
20/01/2008 18:35
Dernière modification de la notice
20/08/2019 16:10
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