Recent advances upper gastrointestinal lymphomas: molecular updates and diagnostic implications.
Détails
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_A08FD6F43D89
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Recent advances upper gastrointestinal lymphomas: molecular updates and diagnostic implications.
Périodique
Histopathology
ISSN
1365-2559 (Electronic)
ISSN-L
0309-0167
Statut éditorial
Publié
Date de publication
01/2021
Peer-reviewed
Oui
Volume
78
Numéro
1
Pages
187-214
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Approximately one-third of extranodal non-Hodgkin lymphomas involve the gastrointestinal (GI) tract, with the vast majority being diagnosed in the stomach, duodenum, or proximal small intestine. A few entities, especially diffuse large B-cell lymphoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue, represent the majority of cases. In addition, there are diseases specific to or characteristic of the GI tract, and any type of systemic lymphoma can present in or disseminate to these organs. The recent advances in the genetic and molecular characterisation of lymphoid neoplasms have translated into notable changes in the classification of primary GI T-cell neoplasms and the recommended diagnostic approach to aggressive B-cell tumours. In many instances, diagnoses rely on morphology and immunophenotype, but there is an increasing need to incorporate molecular genetic markers. Moreover, it is also important to take into consideration the endoscopic and clinical presentations. This review gives an update on the most recent developments in the pathology and molecular pathology of upper GI lymphoproliferative diseases.
Mots-clé
MALT lymphoma, differential diagnosis, duodenum, enteropathy-associated T-cell lymphoma, fluorescent in situ hybridization, gastrointestinal lymphomas, indolent lymphoproliferative disorders, molecular pathology, small intestine, stomach, fluorescent in situ hybridization
Pubmed
Web of science
Open Access
Oui
Création de la notice
10/01/2021 12:16
Dernière modification de la notice
21/11/2022 9:28