Activation of the human hippocampal formation during auditory-verbal long-term memory function.

Détails

ID Serval
serval:BIB_9FEF48054A33
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Activation of the human hippocampal formation during auditory-verbal long-term memory function.
Périodique
Neuroscience Letters
Auteur(s)
Grasby P.M., Frith C.D., Friston K., Frackowiak R.S., Dolan R.J.
ISSN
0304-3940 (Print)
ISSN-L
0304-3940
Statut éditorial
Publié
Date de publication
1993
Volume
163
Numéro
2
Pages
185-188
Langue
anglais
Notes
Publication types: Comparative Study ; Journal ArticlePublication Status: ppublish
Résumé
Clinical data from brain-damaged patients implicates the human hippocampal formation in memory function. We tested the hypothesis that long-term memory function is associated with activation of the hippocampal formation in humans by measuring regional cerebral blood flow changes whilst subjects performed memory tasks. Bilateral hippocampal regional cerebral blood flow was significantly correlated with a measure of the engagement of long-term auditory-verbal memory. No such association was observed for the degree of engagement of auditory-verbal subspan memory. These data provide, for the first time, direct in vivo evidence for the involvement of the hippocampal formation in long-term memory in the intact human brain.
Mots-clé
Adult, Auditory Perception, Hearing, Hippocampus/blood supply, Hippocampus/physiology, Humans, Memory/physiology, Memory, Short-Term/physiology, Oxygen Radioisotopes/diagnostic use, Reference Values, Regional Blood Flow, Speech, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
22/09/2011 17:18
Dernière modification de la notice
20/08/2019 15:06
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