PET/CT in thyroid nodule and differentiated thyroid cancer patients. The evidence-based state of the art.

Détails

ID Serval
serval:BIB_9F432EC6CEB9
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
PET/CT in thyroid nodule and differentiated thyroid cancer patients. The evidence-based state of the art.
Périodique
Reviews in endocrine & metabolic disorders
Auteur⸱e⸱s
Piccardo A., Trimboli P., Foppiani L., Treglia G., Ferrarazzo G., Massollo M., Bottoni G., Giovanella L.
ISSN
1573-2606 (Electronic)
ISSN-L
1389-9155
Statut éditorial
Publié
Date de publication
03/2019
Peer-reviewed
Oui
Volume
20
Numéro
1
Pages
47-64
Langue
anglais
Notes
Publication types: Journal Article ; Review
Publication Status: ppublish
Résumé
A more conservative approach to the clinical management of thyroid nodules and differentiated thyroid cancer has recently been proposed by the 2015 ATA guidelines. In this context, fine-needle aspiration biopsy has been reserved for nodules with particular ultrasound features or dimensions that exclude low-risk thyroid lesions. Accordingly, a less aggressive surgical approach (i.e. lobectomy) has been recommended as the first-choice treatment in nodules with indeterminate cytology or in small cytologically confirmed malignant nodules. At the same time, radioactive remnant ablation has been considered only for DTC patients with concrete risks of disease persistence/relapse after thyroidectomy. In addition, further radioactive iodine therapies (RAI) have been proposed only for patients presenting unresectable and iodine-avid structural relapse. In this complex scenario, which requires attention to each clinical aspect of the patient, the introduction of accurate diagnostic tools is highly warranted. PET/CT is a very sensitive and specific diagnostic procedure that can better characterize the risk of thyroid nodules, identify DTC relapse early and predict the response to RAI. Thus, it seems essential to customize a more conservative approach to thyroid nodules and DTC patients. The aim of this review is to report the principal clinical context in which PET/CT has been used and to evaluate the evidence-based support for each diagnostic indication.
Mots-clé
Animals, Humans, Positron Emission Tomography Computed Tomography/methods, Thyroid Neoplasms/diagnostic imaging, Thyroid Nodule/diagnostic imaging, Diagnosis, Differentiated thyroid Cancer, PET/CT, Thyroid nodules
Pubmed
Web of science
Création de la notice
15/04/2019 7:38
Dernière modification de la notice
27/04/2020 5:20
Données d'usage