Irvine-Gass Macular Edema Responding to the Combination of Oral Mineralocorticoid-Receptor Antagonist With Dexamethasone Drops.

Détails

ID Serval
serval:BIB_9D517A309D1C
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Irvine-Gass Macular Edema Responding to the Combination of Oral Mineralocorticoid-Receptor Antagonist With Dexamethasone Drops.
Périodique
Ophthalmic surgery, lasers & imaging retina
Auteur(s)
Matet A., Daruich A., Behar-Cohen F.
ISSN
2325-8179 (Electronic)
ISSN-L
2325-8160
Statut éditorial
Publié
Date de publication
01/11/2017
Peer-reviewed
Oui
Volume
48
Numéro
11
Pages
936-942
Langue
anglais
Notes
Publication types: Case Reports ; Journal Article
Publication Status: ppublish
Résumé
Long-lasting postoperative macular edema is a therapeutic challenge. The authors report an efficient combination therapy of oral mineralocorticoid receptor antagonists (eplerenone [Inspra; Pfizer, New York City, NY] or spironolactone, 25 mg/day to 50 mg/day) and topical dexamethasone (four times/day and progressive dose tapering) in three refractory cases following complex cataract or retinal detachment surgery. In Case 1, central macular thickness (CMT) decreased from 523 μm to 214 μm and visual acuity (VA) improved from 20/200 to 20/50 during a 6-month period. In Cases 2 and 3, CMT improved from 505 μm to 333 μm and from 438 μm to 316 μm during 5- and 3-month periods, respectively; however, VA remained unchanged (20/100 and 20/200) due to photoreceptor damage. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:936-942.].

Mots-clé
Administration, Oral, Administration, Topical, Aged, Aged, 80 and over, Dexamethasone/therapeutic use, Drug Therapy, Combination, Female, Glucocorticoids/therapeutic use, Humans, Macular Edema/diagnosis, Macular Edema/drug therapy, Male, Mineralocorticoid Receptor Antagonists/therapeutic use, Ophthalmic Solutions, Spironolactone/analogs & derivatives, Spironolactone/therapeutic use, Tomography, Optical Coherence
Pubmed
Web of science
Création de la notice
08/01/2018 17:49
Dernière modification de la notice
20/08/2019 15:03
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