Fusion of erythrocytes by Sendai virus studied by immuno-freeze-etching.

Détails

ID Serval
serval:BIB_9D067BAAE8A9
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Fusion of erythrocytes by Sendai virus studied by immuno-freeze-etching.
Périodique
Journal of Virology
Auteur⸱e⸱s
Bächi T., Aguet M., Howe C.
ISSN
0022-538X (Print)
ISSN-L
0022-538X
Statut éditorial
Publié
Date de publication
1973
Volume
11
Numéro
6
Pages
1004-1012
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Extensive fusion of human erythrocytes agglutinated by Sendai virus was observed after 30 s of incubation at 37 C. Electron microscopy of thin sections failed to reveal the presence of virions, viral fragments, or discrete viral antigens reactive with ferritin-labeled antibody at the sites of fusion. Immuno-freezeetching of membrane surfaces demonstrated the dispersal of viral envelope antigens from what appeared to be original sites of viral attachment. Virus-induced clustering of membrane glycoproteins was interpreted as resulting from interaction of viral antigens with membrane receptor proteins and forming the structural basis for fusion of membranes with one another.
Mots-clé
Absorption, Agglutination, Animals, Antibodies, Viral, Antigens, Viral/isolation & purification, Cell Fusion, Cell Membrane/immunology, Erythrocytes/cytology, Erythrocytes/immunology, Ferritins, Freeze Etching, Glycoproteins, Humans, Immune Sera, Methods, Microscopy, Electron, Models, Structural, Parainfluenza Virus 1, Human/immunology, Rabbits/immunology, Temperature
Pubmed
Web of science
Création de la notice
28/01/2008 11:37
Dernière modification de la notice
20/08/2019 15:03
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