Agglutinines froides et cryoglobulinemie chez un patient avec une hepatite C. [Cold agglutinins and cryoglobulinemia in a patient with hepatitis C]
Détails
ID Serval
serval:BIB_9CEB704E8652
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Agglutinines froides et cryoglobulinemie chez un patient avec une hepatite C. [Cold agglutinins and cryoglobulinemia in a patient with hepatitis C]
Périodique
Presse Médicale
ISSN
0755-4982 (Print)
Statut éditorial
Publié
Date de publication
10/1996
Volume
25
Numéro
32
Pages
1548-9
Notes
Case Reports
English Abstract
Journal Article --- Old month value: Oct 26
English Abstract
Journal Article --- Old month value: Oct 26
Résumé
OBJECTIVES: Cold agglutinins and cryoglobulins are uncommon in the same patient as observed in our case. CASE REPORT: A 74-year-old patient suffered repeated episodes of hemolytic anemia for one year and had hepatitis C anti-virus antibodies. Mixed cryoglobulinemia was found at levels which increased during episodes of acute hemolysis in addition to anti-I cold agglutinins. Two-dimensional electrophoresis revealed identical oligoclonal cold agglutinins and cryoglobulins. DISCUSSION: Unlike mixed cryoglobulinemia, cold agglutinins are not known to occur subsequent to hepatitis C infection. The identical immunoglobulins observed in our patient suggest a common origin. Chronic anti-I cold oligoclonal agglutinins are rarely observed and could be an intermediary step towards monoclonal lymphopathy as has been described in prolonged hepatitis C infection.
Mots-clé
Aged
Agglutinins/*analysis
Anemia, Hemolytic/complications/immunology
Cold
Cryoglobulinemia/*complications/immunology
Cryoglobulins/analysis
Female
Hepatitis C/*complications/immunology
Humans
Time Factors
Pubmed
Web of science
Création de la notice
25/01/2008 16:34
Dernière modification de la notice
20/08/2019 16:03