Bone Texture Assessment on Lateral VFAs Using the Texture Research Investigational Platform (TRIP) and its Fracture Discrimination Ability.
Détails
ID Serval
serval:BIB_9BDC1AA37ADE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Bone Texture Assessment on Lateral VFAs Using the Texture Research Investigational Platform (TRIP) and its Fracture Discrimination Ability.
Périodique
Journal of clinical densitometry
ISSN
1094-6950 (Print)
ISSN-L
1094-6950
Statut éditorial
Publié
Date de publication
2022
Peer-reviewed
Oui
Volume
25
Numéro
4
Pages
599-605
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't
Publication Status: ppublish
Publication Status: ppublish
Résumé
Texture Research Imaging Platform applies trabecular bone score (TBS) measurement principles to images acquired with multiple modalities to assess bone texture at various skeletal sites. This study aimed to assess the bone texture score in dual-energy X-ray absorptiometry-acquired lateral vertebral fracture assessment (VFA) images (BTS <sub>VFA</sub> ), evaluate its reproducibility, and vertebral fracture discrimination ability. Subjects included 178 VF cases and 178 non-VF controls, 136 women and 42 men in each group, age 55-92 years, from two research centers. Cases and controls were matched for age (±5 years), body mass index (±5 kg/m <sup>2</sup> ) and TBS. All participants underwent dual-energy X-ray absorptiometry TBS assessment from standard posterior-anterior lumbar spine scans and BTS <sub>VFA</sub> assessment. VF presence was determined using VFA images applying the Genant's method. BTS <sub>VFA</sub> was lower among fractured women compared to non-fractured (0.626 ± 0.109 vs 0.675 ± 0.099, p < 0.01), but not among men. In a binary logistic regression adjusted for study center and sex, for each SD lower BTS <sub>VFA</sub> , there was a 40% increase (OR 1.40, 95% CI (1.13-1.74)) in the risk of having a prevalent VF; area under the curve (95% CI) 0.616 (0.557-0.675). Inter-assessor and inter-centers ICCs for BTS <sub>VFA</sub> measurements were very good; 0.96 (0.64-0.99) and 0.98 (0.95-0.99), respectively. The BTS <sub>VFA</sub> precision (coefficient of variation) was 2.42%. This feasibility study demonstrates the potential to assess trabecular bone texture in lateral VFA images with good reproducibility. BTS <sub>VFA</sub> can discriminate between fractured and non-fractured women independent of their age, body mass index and TBS. In conclusion, BTS <sub>VFA</sub> , a potential trabecular texture assessment that excludes the posterior elements, may have value in fracture prediction or as a novel approach to be further investigated in spine surgery planning.
Mots-clé
Male, Female, Humans, Middle Aged, Aged, Aged, 80 and over, Spinal Fractures/diagnostic imaging, Reproducibility of Results, Absorptiometry, Photon/methods, Fractures, Bone, Lumbar Vertebrae/diagnostic imaging, Bone Density, Osteoporotic Fractures, Risk Assessment/methods, Bone texture score, dual-energy X-ray absorptiometry, osteoporosis, trabecular bone score, vertebral fracture
Pubmed
Web of science
Création de la notice
25/04/2022 11:22
Dernière modification de la notice
21/11/2023 8:10