Association of sunbed use with skin cancer risk factors in Europe: an investigation within the Euromelanoma skin cancer prevention campaign.
Détails
ID Serval
serval:BIB_9B4DB7AE190A
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Association of sunbed use with skin cancer risk factors in Europe: an investigation within the Euromelanoma skin cancer prevention campaign.
Périodique
Journal of the European Academy of Dermatology and Venereology
Collaborateur⸱rice⸱s
Euromelanoma Working Group,
Contributeur⸱rice⸱s
Baltas E., Bogomolets O., Girnita A., Hafner J., Hercogová J., Konno P., Lorentzen H.F., Maselis T., Medenica L., Mekokishvili L., Murphy M., Nedelciuc B., Oláh J., Onsun N., Pallouras A., Placek W., Potekaev N., Reusch M., Roscher I., Ručigaj T., Scerri L., Šitum M., Zafirovik Z.
ISSN
1468-3083 (Electronic)
ISSN-L
0926-9959
Statut éditorial
Publié
Date de publication
03/2019
Peer-reviewed
Oui
Volume
33 Suppl 2
Pages
76-88
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Publication Status: ppublish
Résumé
Sunbed use has been significantly associated with increased risk of melanoma and non-melanoma skin cancer (NMSC), but its relationship with melanoma's risk factors such as high nevus count, atypical nevi and lentigines is poorly studied. Euromelanoma is a skin cancer prevention campaign conducted all over Europe. It offers a once-a-year screening during which participants' data, including sunbed use and phenotype, are collected via questionnaires.
To investigate the association of sunbed use with nevus count, atypical nevi, lentigines and suspicion of skin cancer.
To ensure reliability of the data, we defined inclusion and exclusion criteria for countries' eligibility for the risk analysis. Multivariate logistic regression models (including age, gender, education, skin type, family history of melanoma, personal history of skin cancer, any sun exposure and any sunscreen use) were used to calculate summary odds ratios (SORs) of each clinical endpoint for ever sunbed use.
Overall, 227 888 individuals from 30 countries completed the Euromelanoma questionnaire. After the data quality check, 16 countries were eligible for the multivariate analysis, for a total of 145 980 participants (64.8% females; median age 43 years; 62.3% highly educated; 28.5% skin type I-II; 11.0% ever sunbed use). Ever sunbed use was independently associated with nevus count >50 [SOR = 1.05 (1.01-1.10)], atypical nevi [SOR = 1.04 (1.00-1.09)], lentigines [SOR = 1.16 (1.04-1.29)] and suspicion of melanoma [SOR = 1.13 (1.00-1.27)]. Conversely, no significant association was found between ever sunbed use and suspicion of NMSC [SOR = 1.00 (0.91-1.10)].
Indoor tanning is significantly associated with well-recognized risk factors for melanoma (including high nevus count, presence of atypical nevi and lentigines) as well as suspicion of melanoma within the Euromelanoma screenees. In order to reduce the prevalence of melanoma risk factors, avoidance/discontinuation of sunbed use should always be encouraged, especially but not exclusively for individuals with high-risk phenotypes.
To investigate the association of sunbed use with nevus count, atypical nevi, lentigines and suspicion of skin cancer.
To ensure reliability of the data, we defined inclusion and exclusion criteria for countries' eligibility for the risk analysis. Multivariate logistic regression models (including age, gender, education, skin type, family history of melanoma, personal history of skin cancer, any sun exposure and any sunscreen use) were used to calculate summary odds ratios (SORs) of each clinical endpoint for ever sunbed use.
Overall, 227 888 individuals from 30 countries completed the Euromelanoma questionnaire. After the data quality check, 16 countries were eligible for the multivariate analysis, for a total of 145 980 participants (64.8% females; median age 43 years; 62.3% highly educated; 28.5% skin type I-II; 11.0% ever sunbed use). Ever sunbed use was independently associated with nevus count >50 [SOR = 1.05 (1.01-1.10)], atypical nevi [SOR = 1.04 (1.00-1.09)], lentigines [SOR = 1.16 (1.04-1.29)] and suspicion of melanoma [SOR = 1.13 (1.00-1.27)]. Conversely, no significant association was found between ever sunbed use and suspicion of NMSC [SOR = 1.00 (0.91-1.10)].
Indoor tanning is significantly associated with well-recognized risk factors for melanoma (including high nevus count, presence of atypical nevi and lentigines) as well as suspicion of melanoma within the Euromelanoma screenees. In order to reduce the prevalence of melanoma risk factors, avoidance/discontinuation of sunbed use should always be encouraged, especially but not exclusively for individuals with high-risk phenotypes.
Mots-clé
Adult, Carcinoma, Basal Cell/epidemiology, Carcinoma, Squamous Cell/epidemiology, Europe/epidemiology, Female, Humans, Lentigo/epidemiology, Male, Middle Aged, Nevus/epidemiology, Nevus/pathology, Risk Factors, Skin Neoplasms/epidemiology, Skin Neoplasms/pathology, Skin Neoplasms/prevention & control, Sunbathing/statistics & numerical data, Surveys and Questionnaires, Tumor Burden
Pubmed
Web of science
Open Access
Oui
Création de la notice
17/03/2019 17:01
Dernière modification de la notice
20/08/2019 16:02