Hamodynamische Auswirkungen der Implantation eines intrakavalen Gasaustauschers. [Hemodynamic effects of the implantation of an intracaval oxygenator]

Détails

ID Serval
serval:BIB_9ABF69D5CDC2
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Hamodynamische Auswirkungen der Implantation eines intrakavalen Gasaustauschers. [Hemodynamic effects of the implantation of an intracaval oxygenator]
Périodique
Schweizerische Medizinische Wochenschrift
Auteur⸱e⸱s
von Segesser  L. K., Pasic  M., Lachat  M., Leskosek  B., Spiess  M., Turina  M. I.
ISSN
0036-7672
Statut éditorial
Publié
Date de publication
04/1993
Peer-reviewed
Oui
Volume
123
Numéro
13
Pages
600-2
Notes
English Abstract
Journal Article --- Old month value: Apr 3
Résumé
Treatment of severe respiratory failure by extracorporeal membrane oxygenation (ECMO) is complex. However, there is now an intravascular gas exchanger (IVOX) available that provides extrapulmonary gas transfer without requiring an extracorporeal blood path. The present study was performed to determine the hemodynamic effects resulting from the intracaval placement of the intravascular device. A bovine model (n = 6; body-weight = 72 +/- 5 kg) was selected for temporary lung support with the intravascular device. The latter was placed in the caval axis under fluoroscopic control after full instrumentation of the animal for hemodynamic measurements including a pulmonary artery catheter for determination of cardiac output by thermodilution and continuous readout of mixed venous oxygen saturation. All measurements were taken after a stabilization period of 15 min. The heart rate moved from 65 +/- 8 before to 72 +/- 10 after implantation and 68 +/- 9 after onset of intravascular gas exchange (NS). Right atrial pressure was 13 +/- 3 mm Hg before, 12 +/- 3 mm Hg after implantation and 10 +/- 3 mm Hg after onset (NS) whereas femoral venous pressure moved from 14 +/- 3 mm Hg to 17 +/- 4 mm Hg (p < 0.05) and remained at 17 +/- 4 mm Hg after onset. Cardiac output was 5.3 +/- 0.7 l/min before, 5.4 +/- 0.7 l/min after implantation and 5.3 +/- 1.1 l/min after onset (NS) while mixed venous oxygen saturation dropped from 60 +/- 7% to 54 +/- 11% and moved to 57 +/- 11 after onset of the device (NS).(ABSTRACT TRUNCATED AT 250 WORDS)
Mots-clé
Animals Cardiac Output Cattle *Hemodynamics Oxygen/blood *Oxygenators, Membrane *Vena Cava, Superior
Pubmed
Web of science
Création de la notice
14/02/2008 14:18
Dernière modification de la notice
20/08/2019 15:01
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