Mandatory infectious diseases consultation for MRSA bacteremia is associated with reduced mortality.

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Ressource 1Télécharger: 5_24844825_Postprint.pdf (683.77 [Ko])
Etat: Public
Version: Author's accepted manuscript
ID Serval
serval:BIB_9937AA68F089
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Mandatory infectious diseases consultation for MRSA bacteremia is associated with reduced mortality.
Périodique
Journal of Infection
Auteur(s)
Tissot F., Calandra T., Prod'hom G., Taffe P., Zanetti G., Greub G., Senn L.
ISSN
1532-2742 (Electronic)
ISSN-L
0163-4453
Statut éditorial
Publié
Date de publication
2014
Volume
69
Numéro
3
Pages
226-234
Langue
anglais
Notes
Publication types: Journal Article Publication Status: ppublish
Résumé
OBJECTIVES: Although infectious disease (ID) consultation has been associated with lower mortality in Staphylococcus aureus bloodstream infections, it is still not mandatory in many centers. This study aimed at assessing the impact of ID consultation on diagnostic and therapeutic management of methicillin-resistant S. aureus (MRSA) bacteremia.
METHODS: Retrospective cohort study of all patients with MRSA bacteremia from 2001 to 2010. ID consultations were obtained on request between 2001 and 2006 and became mandatory since 2007.
RESULTS: 156 episodes of MRSA bacteremia were included, mostly from central venous catheter (32%) and skin and soft tissue (19%) infections. ID consultation coverage was 58% between 2001 and 2006 and 91% between 2007 and 2010. ID consultation was associated with more echocardiography (59% vs. 26%, p < 0.01), vancomycin trough level measurements (99% vs. 77%, p < 0.01), follow-up blood cultures (71% vs. 50%, p = 0.05), deep-seated infections (43% vs. 16%, p < 0.01), more frequent infection source control (83% vs. 57%, p = 0.03), a longer duration of MRSA-active therapy (median and IQR: 17 days, 13-30, vs. 12, 3-14, p < 0.01) and a 20% reduction in 7-day, 30-day and in-hospital mortality.
CONCLUSIONS: ID consultation was associated with a better management of patients with MRSA bacteremia and a reduced mortality.
Pubmed
Web of science
Open Access
Oui
Création de la notice
23/09/2014 14:55
Dernière modification de la notice
20/08/2019 16:00
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