Localized amyloid light-chain amyloidosis and extramedullary plasmacytoma of the mitral valve.

Détails

ID Serval
serval:BIB_96778D2E88B2
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Localized amyloid light-chain amyloidosis and extramedullary plasmacytoma of the mitral valve.
Périodique
Annals of Thoracic Surgery
Auteur(s)
Roumy A., de Leval L., Niclauss L., Schaefer S.C., Kurtin P., Dogan A., von Segesser L.K., Ruchat P.
ISSN
1552-6259 (Electronic)
ISSN-L
0003-4975
Statut éditorial
Publié
Date de publication
2013
Volume
95
Numéro
5
Pages
1782-1784
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
An unusual case of localized amyloid light-chain (AL) amyloidosis and extramedullary plasmacytoma of the mitral valve is described. The worsening of a mitral regurgitation led to investigations and surgery. The valve presented marked distortion and thickening by type AL amyloid associated with a monotypic CD138+ immunoglobulin lambda plasma cell proliferation. Systemic staging showed a normal bone marrow and no evidence of amyloid deposition in other localizations. The patient's outcome after mitral valve replacement was excellent. To our knowledge, this is the first description of a localized AL amyloidosis as well as of a primary extramedullary plasmacytoma of the mitral valve.
Pubmed
Web of science
Création de la notice
13/05/2013 15:28
Dernière modification de la notice
20/08/2019 14:58
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