Localized amyloid light-chain amyloidosis and extramedullary plasmacytoma of the mitral valve.
Détails
ID Serval
serval:BIB_96778D2E88B2
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Localized amyloid light-chain amyloidosis and extramedullary plasmacytoma of the mitral valve.
Périodique
Annals of Thoracic Surgery
ISSN
1552-6259 (Electronic)
ISSN-L
0003-4975
Statut éditorial
Publié
Date de publication
2013
Volume
95
Numéro
5
Pages
1782-1784
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
An unusual case of localized amyloid light-chain (AL) amyloidosis and extramedullary plasmacytoma of the mitral valve is described. The worsening of a mitral regurgitation led to investigations and surgery. The valve presented marked distortion and thickening by type AL amyloid associated with a monotypic CD138+ immunoglobulin lambda plasma cell proliferation. Systemic staging showed a normal bone marrow and no evidence of amyloid deposition in other localizations. The patient's outcome after mitral valve replacement was excellent. To our knowledge, this is the first description of a localized AL amyloidosis as well as of a primary extramedullary plasmacytoma of the mitral valve.
Pubmed
Web of science
Création de la notice
13/05/2013 16:28
Dernière modification de la notice
20/08/2019 15:58