Effects of a partially hydrolyzed guar gum on intestinal absorption of carbohydrate, protein and fat: a double-blind controlled study in volunteers.

Détails

ID Serval
serval:BIB_9502
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Effects of a partially hydrolyzed guar gum on intestinal absorption of carbohydrate, protein and fat: a double-blind controlled study in volunteers.
Périodique
Clinical Nutrition
Auteur(s)
Alam N.H., Meier R., Rausch T., Meyer-Wyss B., Hildebrand P., Schneider H., Bachmann C., Minder E., Fowler B., Gyr K.
ISSN
0261-5614
Statut éditorial
Publié
Date de publication
1998
Volume
17
Numéro
3
Pages
125-129
Langue
anglais
Notes
Publication types: Clinical Trial ; Journal Article ; Randomized Controlled Trial
Résumé
Some dietary fibres have been shown to affect the rate of absorption of dietary carbohydrate, protein and fat as well as exocrine pancreatic function. The aim of the study was to examine the effect of partially hydrolysed guar gum (BENEFIBER), on normal absorption of glucose, amino acid (arginine) and fat. In addition hepatic, pancreatic, renal and haematological side effects were evaluated. METHODS: A double blind, randomized and cross-over design was used. Each subject served as its own control. Ten healthy male volunteers participated in the study. Each subject was randomly assigned to two different dietary regimes for a period of 7 days each. The study was repeated with the other diet for another 7-day period after an interval of at least 1 week. In one study period the subjects took liquid formula diet without fibre and during the other study period they took the same diet with fibre. RESULTS: The results of the study demonstrated that BENEFIBER did apparently not interfere with the normal absorption of glucose, amino acid and fat. In keeping with these observations, insulin release and exocrine pancreatic function were not affected. Haematological, renal and hepatic toxicity were not observed in association with BENEFIBER consumption. CONCLUSION: We conclude that BENEFIBER is a safe source of soluble fibre.
Mots-clé
Adult, Arginine/metabolism, Cross-Over Studies, Dietary Carbohydrates/pharmacokinetics, Dietary Fats/metabolism, Dietary Proteins/pharmacokinetics, Double-Blind Method, Galactans/pharmacology, Glucose Tolerance Test, Humans, Hydrolysis, Intestinal Absorption/drug effects, Male, Mannans/pharmacology, Pancreas/drug effects, Pancreas/physiology, Plant Gums
Pubmed
Web of science
Création de la notice
19/11/2007 13:48
Dernière modification de la notice
20/08/2019 15:57
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