Early Complications in Kidney Donors and Course of Health-related Quality of Life 12 mo After Donation: An Analysis of the Swiss Organ Living-Donor Health Registry.

Détails

ID Serval
serval:BIB_92321B6AB9A0
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Early Complications in Kidney Donors and Course of Health-related Quality of Life 12 mo After Donation: An Analysis of the Swiss Organ Living-Donor Health Registry.
Périodique
Transplantation direct
Auteur⸱e⸱s
Brügger C., Hunkeler Z., Diebold M., Krättli J., Geiger I., Wehmeier C., Wolff T., Vogt B., Storni F., Golshayan D., Zingg T., de Seigneux S., Haidar F., Binet I., Schnyder A., Hübel K., Müller T., Rössler F., Steiger J., Hirt-Minkowski P.
ISSN
2373-8731 (Print)
ISSN-L
2373-8731
Statut éditorial
Publié
Date de publication
11/2024
Peer-reviewed
Oui
Volume
10
Numéro
11
Pages
e1716
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: epublish
Résumé
Since 1998, the Swiss Organ Living-Donor Health Registry (SOL-DHR) has recorded peri- and postoperative complications of living kidney (LK) donors, as reported by all Swiss transplant centers and has collected follow-up data prospectively.
We analyzed the early complications of 2379 consecutive individuals who donated a kidney between January 1998 and June 2022 and assessed their health-related quality of life (HRQoL) 1 y after donation.
In total, 447 early complications in 404/2379 LK donors (17.0%) were reported to the SOL-DHR. The frequency of donors with major complications (ie, Dindo-Clavien classification 3/4) was 2.4%. In total, 31 donors needed reoperation, and in 13/31 (42%), donors reoperation was necessary because of bleeding complications. Independent risk factors for major early complications were older donor age (P = 0.005) and type of surgical approach (ie, the laparoscopic retroperitoneal compared with laparoscopic transabdominal surgery; P = 0.01), but not sex. We observed a U-shaped association of body mass index, where very low/high body mass indexes had higher odds of major early complications, without reaching statistical significance. Although HRQoL was affected by kidney donation, 96.5% of donors indicated that they would donate their kidney again. The only independent risk factor for low HRQoL based on mental health scores was worsening EB after living kidney donation (P < 0.0001).
Overall, living kidney donation is a safe procedure, however, donor age and type of surgical approach affect the risk of complications. A decline in emotional bonding with the recipient after donation may worsen the quality of life of the donor.
Pubmed
Open Access
Oui
Création de la notice
25/10/2024 13:38
Dernière modification de la notice
26/10/2024 6:12
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