Diagnostic accuracy of interictal source imaging in presurgical epilepsy evaluation: A systematic review from the E-PILEPSY consortium.

Détails

ID Serval
serval:BIB_9221BD581CCD
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Diagnostic accuracy of interictal source imaging in presurgical epilepsy evaluation: A systematic review from the E-PILEPSY consortium.
Périodique
Clinical neurophysiology
Auteur(s)
Mouthaan B.E., Rados M., Boon P., Carrette E., Diehl B., Jung J., Kimiskidis V., Kobulashvili T., Kuchukhidze G., Larsson P.G., Leitinger M., Ryvlin P., Rugg-Gunn F., Seeck M., Vulliémoz S., Huiskamp G., Leijten FSS, Van Eijsden P., Trinka E., Braun KPJ
Collaborateur(s)
E-PILEPSY consortium
ISSN
1872-8952 (Electronic)
ISSN-L
1388-2457
Statut éditorial
Publié
Date de publication
05/2019
Peer-reviewed
Oui
Volume
130
Numéro
5
Pages
845-855
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
Publication Status: ppublish
Résumé
Interictal high resolution (HR-) electric source imaging (ESI) and magnetic source imaging (MSI) are non-invasive tools to aid epileptogenic zone localization in epilepsy surgery candidates. We carried out a systematic review on the diagnostic accuracy and quality of evidence of these modalities.
Embase, Pubmed and the Cochrane database were searched on 13 February 2017. Diagnostic accuracy studies taking post-surgical seizure outcome as reference standard were selected. Quality appraisal was based on the QUADAS-2 framework.
Eleven studies were included: eight MSI (n = 267), three HR-ESI (n = 127) studies. None was free from bias. This mostly involved: selection of operated patients only, interference of source imaging with surgical decision, and exclusion of indeterminate results. Summary sensitivity and specificity estimates were 82% (95% CI: 75-88%) and 53% (95% CI: 37-68%) for overall source imaging, with no statistical difference between MSI and HR-ESI. Specificity is higher when partially concordant results were included as non-concordant (p < 0.05). Inclusion of indeterminate test results as non-concordant lowered sensitivity (p < 0.05).
Source imaging has a relatively high sensitivity but low specificity for identification of the epileptogenic zone.
We need higher quality studies allowing unbiased test evaluation to determine the added value and diagnostic accuracy of source imaging in the presurgical workup of refractory focal epilepsy.
Mots-clé
Brain Mapping/methods, Electroencephalography, Epilepsy/diagnostic imaging, Epilepsy/physiopathology, Epilepsy/surgery, Humans, Magnetic Resonance Imaging, Magnetoencephalography, Sensitivity and Specificity, Sensitivity, Source localization, Specificity, Surgery
Pubmed
Web of science
Création de la notice
07/04/2019 15:26
Dernière modification de la notice
18/02/2020 7:20
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