Cortical and subcortical localization of response to pain in man using positron emission tomography.

Détails

ID Serval
serval:BIB_9204CE8395F1
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Titre
Cortical and subcortical localization of response to pain in man using positron emission tomography.
Périodique
Proceedings of the Royal Society B Biological Sciences
Auteur⸱e⸱s
Jones A.K., Brown W.D., Friston K.J., Qi L.Y., Frackowiak R.S.
ISSN
0962-8452 (Print)
ISSN-L
0962-8452
Statut éditorial
Publié
Date de publication
1991
Volume
244
Numéro
1309
Pages
39-44
Langue
anglais
Notes
Publication types: Journal Article ; Research Support, Non-U.S. Gov'tPublication Status: ppublish
Résumé
A quantitative study of the regional cerebral responses to non-painful and painful thermal stimuli in six normal volunteers has been done by monitoring serial measurements of regional blood flow measured by positron emission tomography (PET). In comparison to a baseline of warm stimulation no statistically significant changes in blood flow were seen in relation to increasing non-painful heat. However, highly significant increases in blood flow were seen in response to painful heat in comparison to non-painful heat. These changes were in the contralateral cingulate cortex, thalamus and lenticular nucleus. These findings are discussed in relation to previous physiological observations of responses to nociceptive stimuli in man and primates.
Mots-clé
Adult, Animals, Brain/physiopathology, Cerebral Cortex/physiopathology, Corpus Striatum/physiopathology, Gyrus Cinguli/physiopathology, Hot Temperature, Humans, Male, Middle Aged, Pain/physiopathology, Thalamus/physiopathology, Tomography, Emission-Computed
Pubmed
Web of science
Création de la notice
06/10/2011 18:22
Dernière modification de la notice
20/08/2019 15:55
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