Results at Up to 30 Years After Ileal Pouch-Anal Anastomosis for Chronic Ulcerative Colitis.

Détails

ID Serval
serval:BIB_915A1D2BD4DE
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Results at Up to 30 Years After Ileal Pouch-Anal Anastomosis for Chronic Ulcerative Colitis.
Périodique
Inflammatory bowel diseases
Auteur(s)
Lightner A.L., Mathis K.L., Dozois E.J., Hahnsloser D., Loftus E.V., Raffals L.E., Pemberton J.H.
ISSN
1536-4844 (Electronic)
ISSN-L
1078-0998
Statut éditorial
Publié
Date de publication
05/2017
Peer-reviewed
Oui
Volume
23
Numéro
5
Pages
781-790
Langue
anglais
Notes
Publication types: Journal Article
Publication Status: ppublish
Résumé
Ileal pouch-anal anastomosis (IPAA) has become the surgical procedure of choice for patients with chronic ulcerative colitis. No study to date has examined functional and quality-of-life outcomes 30 years after pouch construction.
Using data from a prospectively maintained database with annually distributed questionnaires, functional outcomes, pouch complications, and quality of life after IPAA were determined.
Overall, 93.3% of patients had a functioning pouch at 30 years. Stool frequency during the day increased slightly from a mean of 5.7 (SD, 2.3) at 1 year to 6.2 (SD, 2.9) at 30 years (P < 0.001); nighttime frequency also increased slightly from 1.5 (SD, 1.2) to 2.1 (SD, 1.2) (P < 0.001). Pouch outcomes and stool frequency were significantly associated with diagnosis, being worse in patients with Crohn's disease, but were minimally associated with age greater than 65 years. After IPAA, the 30-year cumulative probability of pouchitis, stricture, obstruction, and fistula were 80.2%, 56.7%, 44.0%, and 15.8%, respectively. Quality of life scores remained stable over the 30 years.
IPAA is a durable operation for patients requiring proctocolectomy for chronic ulcerative colitis and indeterminate colitis. The functional outcomes and quality of life remained relatively unchanged over the 30 years after IPAA underscoring the longevity of pouches.

Mots-clé
Adult, Anal Canal/surgery, Anastomosis, Surgical/methods, Colitis, Ulcerative/surgery, Colonic Pouches, Female, Humans, Ileum/surgery, Male, Middle Aged, Proctocolectomy, Restorative, Prognosis, Prospective Studies, Quality of Life, Time Factors
Pubmed
Web of science
Création de la notice
10/09/2017 15:45
Dernière modification de la notice
20/08/2019 15:54
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