Additives contained in drug formulations most frequently prescribed in Switzerland
Détails
ID Serval
serval:BIB_90C91A917F15
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Additives contained in drug formulations most frequently prescribed in Switzerland
Périodique
Annals of Allergy
ISSN
0003-4738 (Print)
Statut éditorial
Publié
Date de publication
01/1989
Volume
62
Numéro
1
Pages
21-5
Notes
Journal Article
Research Support, Non-U.S. Gov't --- Old month value: Jan
Research Support, Non-U.S. Gov't --- Old month value: Jan
Résumé
The presence of substances known to induce pseudoallergic reactions was investigated by means of a questionnaire to the manufacturers of 1,467 frequently administered formulations. Benzoates were found in 15% of the formulations, sorbates in 5.5%, sulfites in 3.8%, and benzalkonium in 3.0%. The occurrence of the seven artificial colours studied was as follows: indigotin 7.8, erythrosine 7.4, sunset yellow 6.6, tartrazine 4.9, quinoline yellow 2.8%, ponceau (new coccine) 2.6, and amaranth 1.7%. A significant risk of exposure to preservatives and dyes likely to induce asthma, urticaria, or other pseudoallergic reactions exists for all individuals taking commercial drug products.
Mots-clé
Benzoates
*Chemistry, Pharmaceutical
Coloring Agents
*Pharmaceutical Preparations
Preservatives, Pharmaceutical
Sorbic Acid
Sulfites
Switzerland
Tartrazine
Pubmed
Web of science
Création de la notice
28/01/2008 11:58
Dernière modification de la notice
20/08/2019 14:54