Intensive immunosuppression in intractable rheumatoid arthritis
Détails
ID Serval
serval:BIB_90C8A2AE58DD
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Intensive immunosuppression in intractable rheumatoid arthritis
Périodique
British Journal of Rheumatology
ISSN
0263-7103 (Print)
Statut éditorial
Publié
Date de publication
11/1986
Volume
25
Numéro
4
Pages
380-3
Notes
Journal Article --- Old month value: Nov
Résumé
Twelve patients with intractable rheumatoid arthritis were treated with antilymphocyte globulin (ALG), prednisolone and a cytotoxic agent, usually azathioprine, and were followed for 1 year. There was a significant (p less than 0.05) improvement in the mean score for early-morning stiffness, grip strength and the severity of nodules and vasculitis at 6 weeks and 3 months when compared to the initial visit. However, in most patients, this benefit was not sustained despite continued cytotoxic and steroid therapy. A rise in the haemoglobin and fall in ESR was maintained throughout the study period.
Mots-clé
Antilymphocyte Serum/*therapeutic use
Arthritis, Rheumatoid/blood/immunology/*therapy
Combined Modality Therapy
Hemoglobins/analysis
Humans
Immunosuppressive Agents/*therapeutic use
Leukocyte Count
Pubmed
Web of science
Création de la notice
25/01/2008 8:39
Dernière modification de la notice
20/08/2019 14:54