Differential patterns of functional and structural plasticity within and between inferior frontal gyri support training-induced improvements in inhibitory control proficiency.

Détails

ID Serval
serval:BIB_90154E3F81CA
Type
Article: article d'un périodique ou d'un magazine.
Collection
Publications
Institution
Titre
Differential patterns of functional and structural plasticity within and between inferior frontal gyri support training-induced improvements in inhibitory control proficiency.
Périodique
Human Brain Mapping
Auteur⸱e⸱s
Chavan C.F., Mouthon M., Draganski B., van der Zwaag W., Spierer L.
ISSN
1097-0193 (Electronic)
ISSN-L
1065-9471
Statut éditorial
Publié
Date de publication
2015
Volume
36
Numéro
7
Pages
2527-2543
Langue
anglais
Notes
Publication types: Journal ArticlePublication Status: ppublish
Résumé
Ample evidence indicates that inhibitory control (IC), a key executive component referring to the ability to suppress cognitive or motor processes, relies on a right-lateralized fronto-basal brain network. However, whether and how IC can be improved with training and the underlying neuroplastic mechanisms remains largely unresolved. We used functional and structural magnetic resonance imaging to measure the effects of 2 weeks of training with a Go/NoGo task specifically designed to improve frontal top-down IC mechanisms. The training-induced behavioral improvements were accompanied by a decrease in neural activity to inhibition trials within the right pars opercularis and triangularis, and in the left pars orbitalis of the inferior frontal gyri. Analyses of changes in brain anatomy induced by the IC training revealed increases in grey matter volume in the right pars orbitalis and modulations of white matter microstructure in the right pars triangularis. The task-specificity of the effects of training was confirmed by an absence of change in neural activity to a control working memory task. Our combined anatomical and functional findings indicate that differential patterns of functional and structural plasticity between and within inferior frontal gyri enhanced the speed of top-down inhibition processes and in turn IC proficiency. The results suggest that training-based interventions might help overcoming the anatomic and functional deficits of inferior frontal gyri manifesting in inhibition-related clinical conditions. More generally, we demonstrate how multimodal neuroimaging investigations of training-induced neuroplasticity enable revealing novel anatomo-functional dissociations within frontal executive brain networks. Hum Brain Mapp 36:2527-2543, 2015. © 2015 Wiley Periodicals, Inc.
Pubmed
Web of science
Création de la notice
26/03/2015 0:10
Dernière modification de la notice
20/08/2019 14:53
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