Formation of Peyer's patches
Détails
ID Serval
serval:BIB_8E0BE4174880
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Synthèse (review): revue aussi complète que possible des connaissances sur un sujet, rédigée à partir de l'analyse exhaustive des travaux publiés.
Collection
Publications
Institution
Titre
Formation of Peyer's patches
Périodique
Current Opinion in Genetics and Development
ISSN
0959-437X (Print)
Statut éditorial
Publié
Date de publication
10/2001
Volume
11
Numéro
5
Pages
561-7
Notes
Journal Article
Research Support, Non-U.S. Gov't
Review --- Old month value: Oct
Research Support, Non-U.S. Gov't
Review --- Old month value: Oct
Résumé
Formation of Peyer's patches requires complex interactions between the gut epithelium, the mesenchyme, and bone-marrow-derived hematopoietic progenitors. The first Peyer's patches anlage appear around embryonic day 15.5, when the endoderm has undergone transition to a simple epithelium, the lymphatic vessels have reached the intestinal mucosa, and mesenchymal cells have started to form clusters. Recent data using knockout mice provide insight into the molecular nature of the signals that mediate Peyer's patch ontogeny. These include members of the tumor-necrosis factor family and homeostatic chemokines.
Mots-clé
Animals
Blood Cells/metabolism
Cell Differentiation
Chemokines/metabolism
*Embryonic and Fetal Development
Epithelium/metabolism
Gene Expression Regulation, Developmental
Genes, Homeobox/genetics
Humans
Intestines/blood supply/cytology/embryology/metabolism
Mesoderm/metabolism
Peyer's Patches/blood supply/cytology/*embryology/*metabolism
Signal Transduction
Tumor Necrosis Factor-alpha/metabolism
Pubmed
Web of science
Création de la notice
25/01/2008 16:05
Dernière modification de la notice
20/08/2019 15:52