[Contents] Historical Background and Epidemiology. - Radiological Diagnosis of Pancreatic Neuroendocrine Neoplasms. - The Role of Nuclear Medicine in the Diagnosis of Pancreatic Neuroendocrine Neoplasms. - Endocrinological Approach to the Diagnosis of Pancreatic Neuroendocrine Neoplasms. - Cytological Diagnosis of Pancreatic Neuroendocrine Neoplasms / M. Bongiovanni, Christine Sempoux, Antoine Nobile. - Classification and Staging of Pancreatic Neuroendocrine Neoplasms. - Immunohistochemical Approach to the Diagnosis and Prognostic Evaluation of Pancreatic Neuroendocrine Neoplasms. - Insulinoma. - Glucagonoma. - Somatostatin-Producing Tumor. - VIPoma. - Gastrinoma. - ACTH-Producing Tumor. - Serotonin-Producing Tumor. - Pancreatic Neuroendocrine Tumors Producing GHRH, GH, Ghrelin, PTH, or PTHrP. - Nonfunctioning Pancreatic Neuroendocrine Neoplasms (Including PP-Producing and Calcitonin-Producing Tumors). - Poorly Differentiated Neuroendocrine Carcinoma of the Pancreas. - Mixed Adenoneuroendocrine Carcinoma of the Pancreas. - Hyperplastic and Microadenomatous Pancreatic Neuroendocrine Lesions. - Molecular Pathology of Pancreatic Neuroendocrine Neoplasms. - Surgical Therapy of Pancreatic Neuroendocrine Neoplasms. - Medical Therapy of Pancreatic Neuroendocrine Neoplasms