Case report - coronary vasospasm in transplanted heart: a puzzling phenomenon.
Détails
Etat: Public
Version: Final published version
Licence: CC BY 4.0
ID Serval
serval:BIB_8CA43C739CAC
Type
Article: article d'un périodique ou d'un magazine.
Sous-type
Etude de cas (case report): rapporte une observation et la commente brièvement.
Collection
Publications
Institution
Titre
Case report - coronary vasospasm in transplanted heart: a puzzling phenomenon.
Périodique
BMC cardiovascular disorders
ISSN
1471-2261 (Electronic)
ISSN-L
1471-2261
Statut éditorial
Publié
Date de publication
19/12/2019
Peer-reviewed
Oui
Volume
19
Numéro
1
Pages
305
Langue
anglais
Notes
Publication types: Case Reports ; Video-Audio Media
Publication Status: epublish
Publication Status: epublish
Résumé
Coronary artery spasm (CAS) is an underdiagnosed disease especially in heart transplant patients, and in those patients the etiology and pathophysiology remain largely unknown, although it has been associated with cardiac allograft vasculopathy or graft rejection.
We report the case of a heart-transplant patient whose cardiac graft experienced two coronary vasospasms: the first before transplantation, and the other at one-month of a postoperative course complicated by primary graft failure.
Our case illustrates that a transplanted heart predisposed with coronary vasospasm may suffer from early relapse in the recipient despite of complete post-surgical autonomic denervation. Exacerbated endothelial dysfunction of the donor heart after transplant, with the addition of systemic factors in the recipient may be involved in the genesis of this puzzling phenomenon.
We report the case of a heart-transplant patient whose cardiac graft experienced two coronary vasospasms: the first before transplantation, and the other at one-month of a postoperative course complicated by primary graft failure.
Our case illustrates that a transplanted heart predisposed with coronary vasospasm may suffer from early relapse in the recipient despite of complete post-surgical autonomic denervation. Exacerbated endothelial dysfunction of the donor heart after transplant, with the addition of systemic factors in the recipient may be involved in the genesis of this puzzling phenomenon.
Mots-clé
Coronary Vasospasm/diagnostic imaging, Coronary Vasospasm/etiology, Coronary Vasospasm/physiopathology, Coronary Vasospasm/therapy, Heart Transplantation/adverse effects, Humans, Male, Middle Aged, Primary Graft Dysfunction/diagnostic imaging, Primary Graft Dysfunction/etiology, Primary Graft Dysfunction/physiopathology, Primary Graft Dysfunction/therapy, Recovery of Function, Recurrence, Risk Factors, Time Factors, Treatment Outcome, Cardiac allograft vasculopathy, Coronary artery spasm, Endothelial dysfunction, Heart transplant, Myocardial ischemia, Ventricular tachycardia
Pubmed
Web of science
Open Access
Oui
Création de la notice
03/01/2020 17:19
Dernière modification de la notice
30/04/2021 7:12